Karna Sunaina Tejpal, Panda Rajesh, Maurya Ajeet Pratap, Kumari Shashi
Department of Anesthesiology and Critical Care, All India Institute of Medical Sciences, Saket Nagar, Bhopal, India.
Department of Surgery, All India Institute of Medical Sciences, Bhopal, India.
Indian J Surg. 2020 Dec;82(6):1235-1237. doi: 10.1007/s12262-020-02638-5. Epub 2020 Oct 19.
The COVID-19 disease caused by novel coronavirus was first reported in Wuhan, China, in December 2019 with 5% patients having severe lung injury. Though this disease primarily presents as a lower respiratory tract infection, multiple digestive manifestations have been reported which are often overlooked. The present case report describes the unusual progression of COVID-19 disease from pneumonia to a procoagulant state leading to superior mesenteric artery thrombosis and subsequent gut ischemia necessitating emergency laparotomy. Coagulopathy in COVID-19 is due to an imbalance in the coagulation homeostasis with increase in prothrombin time, fibrinogen, and D-dimers. Early recognition of abdominal symptoms, diagnosis of pathology, and timely surgical intervention may definitely improve outcome. In the management of any patient with COVID-19 disease, we advocate a comprehensive integrated approach with early recognition of digestive symptoms and their timely intervention which should run parallel to the respiratory management.
2019年12月,中国武汉首次报告了由新型冠状病毒引起的COVID-19疾病,5%的患者有严重肺损伤。尽管这种疾病主要表现为下呼吸道感染,但已有多种消化系统表现的报告,这些表现常被忽视。本病例报告描述了COVID-19疾病从肺炎发展到促凝状态,导致肠系膜上动脉血栓形成及随后的肠道缺血,从而需要紧急剖腹手术的不寻常病程。COVID-19中的凝血病是由于凝血稳态失衡,凝血酶原时间、纤维蛋白原和D-二聚体增加。早期识别腹部症状、诊断病理并及时进行手术干预肯定可以改善预后。在任何COVID-19疾病患者的管理中,我们提倡采用综合方法,早期识别消化系统症状并及时进行干预,这应与呼吸管理并行。