Alali Abdulhadi A, Baqais Mohammed O, Albishi Fayez M, Alkhamis Asmaa I, Alshehri Yusuf A, Amri Khadijah F, Albenayan Rana F, Khudeer Shifa A, Anbarserri Muayad M, Alsharif Mohammed S, Hakami Safiah M, Bahammam Manar A, Altooq Noor J, Al-Hawaj Faisal
College of Medicine, Vision Colleges, Riyadh, SAU.
College of Medicine, King Saud University, Riyadh, SAU.
Cureus. 2021 Nov 28;13(11):e19954. doi: 10.7759/cureus.19954. eCollection 2021 Nov.
Thrombotic events are well-recognized complications of coronavirus disease 2019 (COVID-19). The incidence of such complications is highly related to the severity of COVID-19 pneumonia. Recent evidence suggests that the coagulopathy of COVID-19 may persist for some period even after the full recovery from pneumonia. We report the case of a 35-year-old man who presented with a 10-day history of fever and cough. His plain radiograph showed bilateral peripherally located opacities suggestive of COVID-19. The diagnosis was confirmed by the reverse transcriptase-polymerase chain reaction (RT-PCR) for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). He was placed on a non-invasive ventilator but it failed to maintain normal oxygen saturation. Hence, the decision for intubation was made. He was extubated after 10 days in the ICU. The patient had a complete recovery. One week after discharge, the patient presented with severe abdominal pain that was out of proportion to the physical examination findings. He had an abdominal CT scan, which demonstrated a large thrombus occluding the superior mesenteric artery. There was no bowel dilatation or focal mural thickening to suggest bowel ischemia. The patient was resuscitated with intravenous fluid hydration. Opioid analgesics were administered to control the pain. After stabilizing the patient, he underwent laparotomy with thrombectomy. The patient tolerated the operation with no complications and had an uneventful recovery. The patient was discharged in good condition with no active issues after four days of hospitalization. The superior mesenteric thrombosis is an unusual complication of COVID-19 pneumonia. This case provides further evidence on the possibility of thrombotic events following the recovery from COVID-19. There is a pressing need for future studies to investigate the role of prophylactic antithrombotic and anticoagulants in patients who recovered from severe COVID-19.
血栓形成事件是2019冠状病毒病(COVID-19)公认的并发症。此类并发症的发生率与COVID-19肺炎的严重程度高度相关。最近的证据表明,COVID-19的凝血病即使在肺炎完全康复后仍可能持续一段时间。我们报告一例35岁男性病例,该患者有10天的发热和咳嗽病史。其胸部X线平片显示双侧周边部位有模糊影,提示COVID-19。通过针对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的逆转录聚合酶链反应(RT-PCR)确诊。他接受了无创通气,但未能维持正常的血氧饱和度。因此,决定进行插管。他在重症监护病房(ICU)10天后拔管。患者完全康复。出院一周后,患者出现严重腹痛,疼痛程度与体格检查结果不符。他进行了腹部CT扫描,结果显示一个大血栓阻塞了肠系膜上动脉。没有肠扩张或局灶性肠壁增厚提示肠缺血。患者通过静脉补液进行复苏。给予阿片类镇痛药控制疼痛。在患者病情稳定后,他接受了剖腹手术并进行了血栓切除术。患者耐受了手术,没有并发症,恢复顺利。住院四天后,患者状况良好出院,没有活动性问题。肠系膜上静脉血栓形成是COVID-19肺炎的一种不寻常并发症。该病例进一步证明了COVID-19康复后发生血栓形成事件的可能性。迫切需要未来的研究来调查预防性抗血栓药物和抗凝剂在从重症COVID-19康复的患者中的作用。