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隐匿性星状神经节副神经节瘤伪装成神经鞘瘤:一场手术噩梦。

Silent stellate ganglion paraganglioma masquerading as schwannoma: A surgical nightmare.

作者信息

Dandpat Saswat Kumar, Rai Survendra Kumar Rajdeo, Shah Abhidha, Goel Naina, Goel Atul H

机构信息

Department of Neurosurgery, King Edward Memorial Hospital, Seth Gordhandas Memorial Hospital, Mumbai, Maharashtra, India.

Department of Pathology, King Edward Memorial Hospital, Seth Gordhandas Memorial Hospital, Mumbai, Maharashtra, India.

出版信息

J Craniovertebr Junction Spine. 2020 Jul-Sep;11(3):240-242. doi: 10.4103/jcvjs.JCVJS_94_20. Epub 2020 Aug 14.

DOI:10.4103/jcvjs.JCVJS_94_20
PMID:33100776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7546059/
Abstract

A 28-year-old normotensive female presented with Horner's syndrome and paresthesia over the left side of the chest. Imaging study showed a large heterogeneous enhancing lesion in short-T1 inversion recovery sequence with flow voids in T2W sequence of magnetic resonance imaging. The lesion was located in the left-sided D1 and D2 regions extending into the neural foramina and apical part of the lung. During surgery, even minimal dissection of the tumor resulted in marked fluctuation in hemodynamic parameters, requiring temporary suspension of the surgery multiple times until hemodynamic parameters were brought under control by the anesthesiologist with drugs. The massive fluctuation in hemodynamic parameters in an unprepared and unanticipated scenario was a challenge for the anesthetist and surgeon. The tumor was radically excised with improvement of paresthesia in the immediate postoperative period, but Horner's syndrome persisted. After 18-months of follow-up, she was relieved of all symptoms including Horner's syndrome. Histopathological examination confirmed our suspicion as paraganglioma.

摘要

一名28岁血压正常的女性出现霍纳综合征及左侧胸部感觉异常。影像学检查显示,磁共振成像的短T1反转恢复序列中有一个大的不均匀强化病变,T2加权序列中有血流空洞。病变位于左侧D1和D2区域,延伸至神经孔和肺尖部。手术过程中,即使对肿瘤进行最小程度的剥离也会导致血流动力学参数显著波动,需要多次暂时中止手术,直到麻醉医生用药将血流动力学参数控制住。在未做准备且未预料到的情况下血流动力学参数出现巨大波动,这对麻醉师和外科医生来说是一个挑战。肿瘤被根治性切除,术后即刻感觉异常有所改善,但霍纳综合征仍持续存在。经过18个月的随访,她所有症状包括霍纳综合征均得到缓解。组织病理学检查证实我们的怀疑,即副神经节瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa3b/7546059/e9e09fbe9605/JCVJS-11-240-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa3b/7546059/fca422a096bf/JCVJS-11-240-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa3b/7546059/296aec668e79/JCVJS-11-240-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa3b/7546059/e9e09fbe9605/JCVJS-11-240-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa3b/7546059/fca422a096bf/JCVJS-11-240-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa3b/7546059/296aec668e79/JCVJS-11-240-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa3b/7546059/e9e09fbe9605/JCVJS-11-240-g003.jpg

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本文引用的文献

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Cervical sympathetic chain paraganglioma: a report of 2 cases and a literature review.颈交感神经链副神经节瘤:2例报告及文献复习
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Important observations made managing carotid body tumors during a 25-year experience.在 25 年的经验中对颈动脉体肿瘤进行管理时的重要观察结果。
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Sympathetic paraganglioma presenting with Horner's syndrome in a child.一名儿童患伴有霍纳综合征的交感神经节细胞瘤。
第五版世界卫生组织头颈部肿瘤分类更新:2022 年世界卫生组织头颈部神经内分泌肿瘤分类概述。
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