Irons G B, Weiland L H, Brown W L
Surg Clin North Am. 1977 Jun;57(3):575-83. doi: 10.1016/s0039-6109(16)41239-9.
Neck tumors developing from the paraganglion system are best called paragangliomas. They may be described further as to site of origin and as to whether they are functioning or nonfunctioning. Review was made of 116 cases in which operation for paraganglioma was performed at the Mayo Clinic. The diagnosis depends upon demonstration of a lateral neck mass, elimination of other causes, and a tumor blush on angiography. Screening tests should be done to determine whether the tumor is producing epinephrine. Surgical management should be selective, depending upon the location and involvement of surrounding structures, particularly the carotid artery system. A conservative approach is indicated for those patients whose tumor surrounds the carotid vessels, because the risk of complications is greater than the risk of leaving the tumor in the neck. Conservatism is also indicated for patients in the older age group, because of the slow growth of these tumors and the low incidence of malignancy.
起源于副神经节系统的颈部肿瘤最好称为副神经节瘤。可根据其起源部位以及是否具有功能进一步描述。对梅奥诊所进行副神经节瘤手术的116例病例进行了回顾。诊断取决于颈部外侧肿块的证实、其他病因的排除以及血管造影显示的肿瘤染色。应进行筛查试验以确定肿瘤是否产生肾上腺素。手术治疗应具有选择性，取决于肿瘤的位置以及周围结构尤其是颈动脉系统的受累情况。对于肿瘤包绕颈动脉血管的患者，应采取保守方法，因为并发症的风险大于将肿瘤留在颈部的风险。对于老年患者也应采取保守方法，因为这些肿瘤生长缓慢且恶性发生率低。
