Han Rui, Guo Gangwen, Ni Yuncheng, Wang Ziyang, Yang Liuqing, Zhang Jianping, Li Xuelian, Hu Rong, Huang Dong, Zhou Haocheng
Department of Pain, The Third Xiangya Hospital and Institute of Pain Medicine, Central South University, Changsha, China.
Hunan Key Laboratory of Brain Homeostasis, Central South University, Changsha, China.
Front Neurosci. 2020 Sep 23;14:574713. doi: 10.3389/fnins.2020.574713. eCollection 2020.
Peripheral nerve stimulation may be an alternative option to treat severe facial pain. We assessed the application of peripheral nerve stimulation for pain management in patients with herpes zoster ophthalmicus.
A retrospective analysis was conducted in patients suffering severe facial pain caused by ophthalmic herpetic lesions. We identified the change in pain severity before and after peripheral nerve stimulation for up to 12 months.
Eighteen patients were enrolled. Their mean age was 70.8 ± 9.5 years. Fifteen patients presented with subacute pain for 1-3 months, and three patients suffered postherpetic neuralgia. Dramatic relief from pain was achieved in 83% of patients (15 out of 18) upon initial removal of the stimulator, with pain reduction of > 50%. The long-term analgesic effect was reported at the 6- and 12-month follow-ups, with reductions in the visual analog scale of 4.8 ± 1.2 ( = 18) and 5.4 ± 1.4 ( = 11), respectively. The prevalence of postherpetic neuralgia was 7% (1 out of 15) in the subacute pain group. No obvious adverse effect was observed.
Peripheral nerve stimulation may be an efficacious and safe approach for pain control in patients with herpes zoster ophthalmicus.
周围神经刺激可能是治疗重度面部疼痛的一种替代选择。我们评估了周围神经刺激在眼部带状疱疹患者疼痛管理中的应用。
对因眼部疱疹性病变导致重度面部疼痛的患者进行回顾性分析。我们确定了周围神经刺激前后长达12个月的疼痛严重程度变化。
纳入18例患者。他们的平均年龄为70.8±9.5岁。15例患者表现为1 - 3个月的亚急性疼痛，3例患者患有带状疱疹后神经痛。在初次移除刺激器时，83%的患者（18例中的15例）疼痛得到显著缓解，疼痛减轻>50%。在6个月和12个月的随访中报告了长期镇痛效果，视觉模拟评分分别降低了4.8±1.2（n = 18）和5.4±1.4（n = 11）。亚急性疼痛组中带状疱疹后神经痛的患病率为7%（15例中的1例）。未观察到明显不良反应。
周围神经刺激可能是眼部带状疱疹患者疼痛控制的一种有效且安全的方法。
