Yu Xiaoyan, Li Yuxi, Tang Li, Deng Lu, Zhao Yuxin, Zhao Xianmei, Xu Huilan, Zeng Ming
Department of Social Medicine and Health Management, Xiangya School of Public Health, Central South University, Changsha, China.
Department of Clinical Nursing, The Second Xiangya Hospital of Central South University, Changsha, China.
Front Psychol. 2020 Sep 25;11:2104. doi: 10.3389/fpsyg.2020.02104. eCollection 2020.
To understand the current pandemic, levels of anxiety in frontline staff, and whether they have been using medication to prevent COVID-19.
Between January 10 and March 10, 2020, 290 frontline staff completed a questionnaire incorporating the Generalized Anxiety Disorder Scale 7 (GAD-7) to indicate their psychological behavior in the use of preventive medication.
Of those who participated in the study, 77.6% used preventive medication, with 47.5, 40.9, and 11.6% using these as part of routine preventive treatment, to fight infection after it was contracted, and after occupational exposure, respectively. There was a statistically significant relationship between the anxiety scale scores and the frequency of medication use ( < 0.05). Comparative analyses revealed that the scores of those in the group taking medication after occupational exposure (to respiratory and blood-borne pathogens) were significantly different from other groups. The proportion of participants choosing Western medicine, traditional Chinese medicine, and integrated Chinese and Western medicine was 24.4, 28.0, and 47.6%, respectively. Additionally, the relationship between the anxiety scale scores and the three types of medication was statistically significant ( < 0.05), as was the difference between Western medicine and other groups. According to Multinomial logistic regression based on the adjustment to gender, age, educational level, marital status, current workplace, and profession, participants with moderate to severe anxiety, had higher odds ( = 10.331, 95%CI:1.453-73.429) of using Western medicine than participants with no anxiety. Participants with moderate anxiety were 6.399 times more likely to use an integrated combination of traditional Chinese and Western medicine compared to those with no anxiety ( = 6.399, 95%CI:1.007-40.658). Furthermore, those with mild anxiety were 2.656 times more likely to use integrated traditional Chinese and Western medicine than those with no anxiety ( = 2.657, 95%CI:1.075-6.570). The probability that frontline medical staff with moderate anxiety took preventive medication after occupational exposure to COVID-19 was 8.066 times ( = 8.066, 95%CI:1.043-62.353) higher than that of staff without anxiety.
This study revealed that there was more anxiety among frontline medical staff who took medication after unexpected occupational exposure. There was less anxiety among those using an integrated course of Chinese and Western medicine than Western medicine alone. It was also observed that anxiety affects the types and frequency of the preventive medication taken. Frontline medical staff who suffer from anxiety are also more likely to use medication to prevent COVID-19.
了解当前的疫情、一线工作人员的焦虑程度，以及他们是否使用药物预防新冠病毒。
2020年1月10日至3月10日期间，290名一线工作人员完成了一份包含广泛性焦虑障碍量表7（GAD - 7）的问卷，以表明他们在使用预防药物方面的心理行为。
参与研究的人员中，77.6%使用了预防药物，其中47.5%、40.9%和11.6%分别将其作为常规预防治疗的一部分、感染后对抗感染以及职业暴露后使用。焦虑量表得分与用药频率之间存在统计学显著关系（<0.05）。比较分析显示，职业暴露（于呼吸道和血源性病原体）后服药组的得分与其他组有显著差异。选择西药、中药和中西医结合药物的参与者比例分别为24.4%、28.0%和47.6%。此外，焦虑量表得分与这三种药物类型之间的关系具有统计学意义（<0.05），西药与其他组之间也存在差异。根据基于性别、年龄、教育水平、婚姻状况、当前工作场所和职业调整的多项逻辑回归分析，中度至重度焦虑的参与者使用西药的几率（=10.331，95%CI：1.453 - 73.429）高于无焦虑的参与者。中度焦虑的参与者使用中西医结合药物的可能性是无焦虑参与者的6.399倍（=6.399，95%CI：1.007 - 40.658）。此外，轻度焦虑的参与者使用中西医结合药物的可能性是无焦虑参与者的2.656倍（=2.657，95%CI：1.075 - 6.570）。中度焦虑的一线医护人员在职业暴露于新冠病毒后服用预防药物的概率比无焦虑的工作人员高8.066倍（=8.066，95%CI：1.043 - 62.353）。
本研究表明，意外职业暴露后服药的一线医护人员焦虑情绪更严重。使用中西医结合药物的人员比仅使用西药的人员焦虑程度更低。还观察到焦虑会影响预防药物使用的类型和频率。患有焦虑症的一线医护人员也更有可能使用药物预防新冠病毒。
