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混合性嗜酸性嫌色细胞瘤自发性破裂:一例报告

Spontaneous rupture of a hybrid oncocytic chromophobe tumor: A case report.

作者信息

Matsuoka Yuki, Matsuda Yoko, Arai Hironobu, Sugimoto Mikio

机构信息

Department of Urology, Faculty of Medicine, Kagawa University, Kagawa, Japan.

Onco-Pathology, Department of Pathology and Host-Defense, Faculty of Medicine, Kagawa University, Kagawa, Japan.

出版信息

Urol Case Rep. 2020 Jun 16;33:101304. doi: 10.1016/j.eucr.2020.101304. eCollection 2020 Nov.

DOI:10.1016/j.eucr.2020.101304
PMID:33102007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7573824/
Abstract

The prognosis of Hybrid oncocytic chromophobe tumor (HOCT) is usually excellent, nevertheless, we are reporting a rare case of HOCT that resulted in death from tumor infection and rupture. Bilateral solid and cystic masses were detected in a 55-year-old woman during a computed tomography examination. HOCT was diagnosed following histopathological examination obtained during needle biopsy. Watchful waiting at another hospital was selected as the treatment strategy. Three years later, she was referred to our hospital in shock and died on the 3rd hospital day. The cause of death was thought to be peritonitis secondary to rupture of an infected HOCT.

摘要

混合性嗜酸性嫌色细胞瘤(HOCT)的预后通常很好,然而,我们报告了一例罕见的HOCT病例,该病例因肿瘤感染和破裂导致死亡。一名55岁女性在计算机断层扫描检查中发现双侧实性和囊性肿块。经针吸活检获得组织病理学检查后诊断为HOCT。选择在另一家医院进行观察等待作为治疗策略。三年后,她因休克被转诊至我院,并于住院第3天死亡。死亡原因被认为是感染性HOCT破裂继发腹膜炎。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9381/7573824/e8ac39584604/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9381/7573824/a6b07d889086/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9381/7573824/f9c722d04160/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9381/7573824/e8ac39584604/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9381/7573824/a6b07d889086/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9381/7573824/f9c722d04160/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9381/7573824/e8ac39584604/gr3.jpg

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本文引用的文献

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Sporadic hybrid oncocytic/chromophobe tumor of the kidney: a clinicopathologic, histomorphologic, immunohistochemical, ultrastructural, and molecular cytogenetic study of 14 cases.肾脏散发性嗜酸细胞瘤/嫌色细胞混合瘤:14 例临床病理、组织形态学、免疫组织化学、超微结构和分子细胞遗传学研究。
Virchows Arch. 2010 Apr;456(4):355-65. doi: 10.1007/s00428-010-0898-4. Epub 2010 Mar 19.
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Birt-Hogg-Dubé syndrome: diagnosis and management.Birt-Hogg-Dubé 综合征:诊断与管理。
Lancet Oncol. 2009 Dec;10(12):1199-206. doi: 10.1016/S1470-2045(09)70188-3.
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Hybrid renal cell carcinomas containing histopathologic features of chromophobe renal cell carcinomas and oncocytomas have excellent oncologic outcomes.
含有嫌色细胞肾细胞癌和嗜酸细胞瘤组织病理学特征的混合性肾细胞癌具有极好的肿瘤学预后。
Eur Urol. 2010 Apr;57(4):661-5. doi: 10.1016/j.eururo.2009.05.009. Epub 2009 May 18.
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Renal oncocytosis: a morphologic study of fourteen cases.肾嗜酸细胞瘤:14例形态学研究
Am J Surg Pathol. 1999 Sep;23(9):1094-101. doi: 10.1097/00000478-199909000-00013.
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Renal cell carcinoma: natural history and results of treatment.肾细胞癌:自然病史与治疗结果
J Urol. 1978 Jun;119(6):722-6. doi: 10.1016/s0022-5347(17)57611-9.