Patel N P, Lavengood R W
J Urol. 1978 Jun;119(6):722-6. doi: 10.1016/s0022-5347(17)57611-9.
We reviewed 166 cases of renal cell carcinoma. The presenting symptoms varied from vague backache to hypovolemic shock. The most common symptoms were pain, hematuria, a palpable mass and hypertension. Most cases involved were clear cell carcinoma (83 per cent) and survival was no better than in cases of granular cell carcinoma. The tumors metastasized to almost every organ of the body. Bilateral simultaneous primary renal cell carcinoma is described in 1 patient, who has survived for more than 5 years. The over-all 5-year survival rates of simple and radical nephrectomy were 32 and 66.6 per cent, respectively. Radiation therapy does not improve survival irrespective of stage. The 5-year survival rate with renal vein involvement was 32 per cent. Nephrectomy in patients with distant metastasis did not alter survival. Among the patients with metastasis 74 per cent were dead before 1 year and 96 per cent before 3 years.
我们回顾了166例肾细胞癌病例。呈现出的症状从模糊的背痛到低血容量性休克不等。最常见的症状是疼痛、血尿、可触及肿块和高血压。大多数病例为透明细胞癌（83%），其生存率并不优于颗粒细胞癌病例。肿瘤转移至身体几乎每个器官。1例双侧同时性原发性肾细胞癌患者已存活5年以上。单纯肾切除术和根治性肾切除术的总体5年生存率分别为32%和66.6%。无论处于何阶段，放疗均不能提高生存率。肾静脉受累患者的5年生存率为32%。远处转移患者行肾切除术并未改变生存率。在有转移的患者中，74%在1年内死亡，96%在3年内死亡。
