Chun Tristen T, Jimenez Juan Carlos, Pantoja Joe L, Moriarty John M, Freeman Shanna
Department of Vascular Surgery, Gonda (Goldschmied) Vascular Center, David Geffen School of Medicine at UCLA, Los Angeles, Calif.
Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, Calif.
J Vasc Surg Cases Innov Tech. 2020 Dec;6(4):653-656. doi: 10.1016/j.jvscit.2020.10.002. Epub 2020 Oct 19.
Patients with acute coronavirus disease 2019 (COVID-19) respiratory infection are associated with concomitant thromboembolic complications and a hypercoagulable state. Although these mechanisms are not completely understood, unique alterations in the serum markers for hemostasis and thrombosis have been detected. A high index of suspicion is required by vascular surgeons for patients presenting with this novel virus. We present the case of a 51-year-old man with acute COVID-19 pneumonia who developed phlegmasia cerulea dolens despite chronic warfarin therapy and a supratherapeutic international normalized ratio.
患有2019年新型冠状病毒病（COVID-19）呼吸道感染的患者常伴有血栓栓塞并发症和高凝状态。尽管这些机制尚未完全明确，但已检测到止血和血栓形成的血清标志物有独特改变。血管外科医生对于感染这种新型病毒的患者需保持高度警惕。我们报告一例51岁男性急性COVID-19肺炎患者，尽管长期服用华法林且国际标准化比值高于治疗范围，但仍发生了股青肿。
