Maternity Teaching Hospital, Erbil City, Kurdistan Region, Iraq.
Department of Obstetrics and Gynaecology, College of Medicine, Hawler Medical University, Erbil City, Kurdistan Region, Iraq.
East Mediterr Health J. 2020 Oct 13;26(10):1285-1293. doi: 10.26719/emhj.20.041.
Data vary on maternal and perinatal outcomes of twin pregnancies conceived through assisted reproductive technology compared with spontaneous conception.
This study compared maternal, perinatal and obstetric outcomes of dichorionic twin pregnancies conceived spontaneously with twin pregnancies conceived through assisted reproductive technology.
This was a cross-sectional study of dichorionic twins delivered at the Maternity Teaching Hospital, Erbil, Kurdistan Region, Iraq from 1 November 2016 to 31 December 2017. Twin pregnancies were classified into two groups: spontaneously conceived (n = 121) and conceived through assisted reproductive technology (n = 79). Maternal and perinatal outcomes were compared between the two groups. The chi-squared test was used to compare categorical variables and the Student t-test to compare means. Logistic regression analysis was used to assess factors associated with admission to the neonatal intensive care unit.
Pregnancy-induced hypertension, gestational diabetes and preterm rupture of membranes were more common in mothers in the assisted reproductive technology group (P < 0.05). Preterm birth, low neonatal birth weight and congenital malformation were also more common in the assisted reproductive technology group (P < 0.001). Gestational age < 33 weeks and conception through assisted reproductive technology were significantly associated with admission to the neonatal intensive care unit for both twins.
Studies are needed to assess the reasons for the differences in perinatal and maternal outcomes between twin pregnancies conceived spontaneously and through assisted reproductive technology.
通过辅助生殖技术受孕的双胞胎与自然受孕的双胞胎相比，其母婴和围产期结局的数据存在差异。
本研究比较了自然受孕的双绒毛膜双胞胎与通过辅助生殖技术受孕的双绒毛膜双胞胎的母婴、围产和产科结局。
这是一项在伊拉克库尔德斯坦地区埃尔比勒教学医院分娩的双绒毛膜双胞胎的横断面研究，时间为 2016 年 11 月 1 日至 2017 年 12 月 31 日。将双胞胎妊娠分为两组：自然受孕（n=121）和通过辅助生殖技术受孕（n=79）。比较两组之间的母婴和围产结局。卡方检验用于比较分类变量，Student t 检验用于比较均值。逻辑回归分析用于评估与新生儿重症监护病房入院相关的因素。
辅助生殖技术组的母亲更常见妊娠高血压、妊娠期糖尿病和胎膜早破（P<0.05）。辅助生殖技术组的早产儿、低新生儿出生体重和先天性畸形也更为常见（P<0.001）。<33 周的胎龄和通过辅助生殖技术受孕与双胞胎均需入住新生儿重症监护病房显著相关。
需要研究来评估自然受孕和通过辅助生殖技术受孕的双胞胎围产期和母婴结局差异的原因。
