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大血管血管炎:18F-FDG PET/CT 成像标准。

Large vessel vasculitis: imaging standards of F-FDG PET/CT.

机构信息

Department of Diagnostic Radiology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan.

出版信息

Jpn J Radiol. 2021 Mar;39(3):225-232. doi: 10.1007/s11604-020-01059-4. Epub 2020 Oct 27.

Abstract

Improvements in positron emission tomography (PET) technology have contributed to increased diagnostic accuracy in patients with large-vessel vasculitis (LVV) over the last decades. Many systematic reviews and meta-analyses were conducted, and earlier diagnosis by F-FDG PET can be made in patients suspected of having LVV. Two subtypes, Takayasu arteritis and giant cell arteritis, will progress when poorly responding to corticosteroids and augmented immunosuppression. In most patients, disease activity cannot be monitored by laboratory tests alone; therefore, glucose metabolism may be a source for possible biomarkers. In this review, we present current concepts regarding F-FDG PET/CT imaging standards.

摘要

过去几十年中,正电子发射断层扫描(PET)技术的改进提高了大动脉炎(LVV)患者的诊断准确性。已经进行了许多系统评价和荟萃分析,通过 F-FDG PET 可以更早地诊断疑似患有 LVV 的患者。两种亚型,即 Takayasu 动脉炎和巨细胞动脉炎,如果对皮质类固醇和增强免疫抑制反应不佳,病情会进展。在大多数患者中,仅通过实验室检查无法监测疾病活动,因此葡萄糖代谢可能是潜在生物标志物的来源。在本综述中,我们提出了有关 F-FDG PET/CT 成像标准的当前概念。

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