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18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描在大血管血管炎诊断和监测中的作用——一篇综述文章。

The role of 18F-fluorodeoxyglucose PET/computed tomography in the diagnosis and monitoring of large vessel vasculitides - a review article.

作者信息

Bahrami Mahshid, Mohammadi Hossein, Mirgaloyebayat Hannaneh, Mohajeri Zahra, Fazeli Pooya, Mojahedi Azad, Afsharirad Ali, Tavakoli Reza, Sadeghian Amirhossein, Nourian Sayed Mohammad Amin

机构信息

Department of Radiology, Isfahan University of Medical Sciences Isfahan, Iran.

School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.

出版信息

Am J Nucl Med Mol Imaging. 2023 Aug 15;13(4):127-135. eCollection 2023.

Abstract

In the last two decades, advancements in positron emission tomography (PET) technology have increased the diagnostic accuracy of patients with large-vessel vasculitis (LVV). Numerous systematic reviews and meta-analyses have been conducted, and patients suspected of having LVV can be diagnosed earlier with 18F-FDG PET. Two subtypes, giant cell arteritis (GCA) and Takayasu arteritis (TA), will progress when their response to corticosteroids and enhanced immunosuppression is inadequate. In the majority of patients, disease activity cannot be monitored solely through laboratory procedures; consequently, glucose metabolism may be a source of potential biomarkers. In this article, we discuss the current state of 18F-FDG PET/CT imaging standards.

摘要

在过去二十年中,正电子发射断层扫描(PET)技术的进步提高了大血管血管炎(LVV)患者的诊断准确性。已经进行了大量的系统评价和荟萃分析,疑似患有LVV的患者可以通过18F-FDG PET更早地得到诊断。巨细胞动脉炎(GCA)和大动脉炎(TA)这两种亚型在对皮质类固醇和强化免疫抑制反应不足时会进展。在大多数患者中,疾病活动不能仅通过实验室检查来监测;因此,葡萄糖代谢可能是潜在生物标志物的一个来源。在本文中,我们讨论了18F-FDG PET/CT成像标准的现状。

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