Department of Epidemiology, Netherlands Institute of Mental Health and Addiction, Utrecht, the Netherlands.
Department of Interdisciplinary Social Sciences, Youth Studies, Utrecht University, Utrecht, the Netherlands.
Depress Anxiety. 2021 Mar;38(3):328-336. doi: 10.1002/da.23103. Epub 2020 Oct 27.
Data on episode duration of anxiety disorders are required for informing patients and for disease management, but such data from population studies are lacking.
Three-year longitudinal data were used from the Netherlands Mental Health Survey and Incidence Study-2, a psychiatric epidemiological cohort study among the general adult population (N = 6646). Respondents with a new (first or recurrent) anxiety disorder were selected (n = 158). DSM-IV diagnoses were assessed with the Composite International Diagnostic Interview; the Life Chart Interview assessed episode duration and recovery rates.
Among those with anxiety disorder, median episode duration was 7.5 months and mean duration was 15.2 months. 38.8% had not recovered at 12 months and 30.1% not at 36 months. Longer duration was associated with older age, not having a paid job, higher neuroticism, more physical disorders, and worse physical functioning.
Also, in the general population, anxiety disorder has a rather chronic course. After 12 months the cumulative recovery rate flattened. To prevent and manage chronicity, timely treatment, and chronic disease management are required. The risk indicators found may help to identify individuals with an anxiety disorder at risk for chronicity.
需要了解焦虑症发作持续时间的数据，以便为患者提供信息和进行疾病管理，但缺乏此类来自人群研究的数据。
使用荷兰精神健康调查和发病率研究-2 的三年纵向数据，这是一项针对普通成年人群（N=6646）的精神病流行病学队列研究。选择了新发（首次或复发性）焦虑症的受访者（n=158）。使用复合国际诊断访谈评估 DSM-IV 诊断；生命图表访谈评估发作持续时间和恢复率。
在患有焦虑症的患者中，发作持续时间的中位数为 7.5 个月，平均持续时间为 15.2 个月。12 个月时，38.8%的患者未恢复，36 个月时，30.1%的患者未恢复。持续时间较长与年龄较大、没有带薪工作、神经质程度较高、更多的身体障碍和身体功能较差有关。
此外，在一般人群中，焦虑症的病程相当长。12 个月后，累积恢复率趋于平稳。为了预防和管理持续性，需要及时治疗和慢性疾病管理。发现的风险指标可能有助于识别有慢性风险的焦虑症患者。
