中性粒细胞与淋巴细胞比值和血小板与淋巴细胞比值在肛门直肠脓肿中的评估。

The evaluation of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in anorectal abscess.

机构信息

Deparment of General Surgery, Ordu University Training and Research Hospital, Ordu-Turkey.

出版信息

Ulus Travma Acil Cerrahi Derg. 2020 Nov;26(6):887-892. doi: 10.14744/tjtes.2020.04501.

DOI:10.14744/tjtes.2020.04501

PMID:33107952

Abstract

BACKGROUND

Anorectal abscess (ARA) is a commonly observed surgical situation. Our aim is to evaluate neutrophil-lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) in ARA.

METHODS

From January 2014 to March 2019, patients diagnosed with ARA were retrospectively analysed, and a patient group was formed. Healthy individuals were included in this study as a control group. The demographic characteristics, completed blood count (CBC) and c-reactive protein (CRP) values of patients were analysed. Localisation of abscess in patients was assessed using computed tomography results. From CBC parameters, white blood count (WBC), NLR and PLR values were identified. The cut-off values for data, sensitivity and specificity were identified using the receiver operating curve (ROC) analyses.

RESULTS

In the patient group, WBC, CRP, NLR and PLR values were identified to be statistically significantly increased (p<0.001). When supralevator abscess localisation was compared with other ARA localisations, there was a statistically significant difference for WBC (p=0.003), but no statistically significant differences were identified for CRP, NLR and PLR (p>0.05). ROC analysis found WBC had cut-off value of 9.99 103/μL for ARA diagnosis with 95% sensitivity and 95% specificity, a CRP had 2.5 mg/dL cut-off value with 88% sensitivity and 95% specificity, NLR had a cut-off of 3.96 with a sensitivity of 82% and specificity of 95% and PLR had a cut-off value of 112.84 with a sensitivity of 71% and specificity of 68%.

CONCLUSION

We believe NLR may be used as a helpful diagnostic marker for ARA diagnosis; however, PLR has low sensitivity and specificity.

摘要

背景

肛门直肠脓肿（ARA）是一种常见的外科情况。我们旨在评估中性粒细胞-淋巴细胞比值（NLR）和血小板-淋巴细胞比值（PLR）在 ARA 中的作用。

方法

回顾性分析 2014 年 1 月至 2019 年 3 月期间诊断为 ARA 的患者，并将其分为患者组。本研究还纳入了健康个体作为对照组。分析患者的人口统计学特征、全血细胞计数（CBC）和 C 反应蛋白（CRP）值。通过计算机断层扫描（CT）结果评估脓肿的定位。从 CBC 参数中确定白细胞计数（WBC）、NLR 和 PLR 值。使用受试者工作特征曲线（ROC）分析确定数据、灵敏度和特异性的截断值。

结果

在患者组中，WBC、CRP、NLR 和 PLR 值均明显升高（p<0.001）。与其他 ARA 定位相比，高位脓肿定位时，WBC 有统计学差异（p=0.003），而 CRP、NLR 和 PLR 无统计学差异（p>0.05）。ROC 分析发现，WBC 的截断值为 9.99 103/μL，对 ARA 诊断具有 95%的敏感性和 95%的特异性，CRP 的截断值为 2.5mg/dL，敏感性为 88%，特异性为 95%，NLR 的截断值为 3.96，敏感性为 82%，特异性为 95%，PLR 的截断值为 112.84，敏感性为 71%，特异性为 68%。