The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA.
Dev Cell. 2020 Oct 26;55(2):120-122. doi: 10.1016/j.devcel.2020.09.028.
During brain development, the daughter cells of neural stem cells have to make a choice - either to become new stem cells or to differentiate into neurons. In a recent issue of Science, Iwata et al. (2020) show that these fate decisions can be determined after mitosis by mitochondrial remodeling.
在大脑发育过程中，神经干细胞的子细胞必须做出选择——要么成为新的干细胞，要么分化为神经元。在最近一期的《科学》杂志上，Iwata 等人（2020）表明，这些命运决定可以在有丝分裂后通过线粒体重塑来确定。
