Doctor, Department of Hematology and Hemotherapy, 28116Federal University of Pernambuco, Pernambuco, Brazil.
Doctor, Department of Hematology and Hemotherapy, Maurício de Nassau University Center, Pernambuco, Brazil.
Trop Doct. 2021 Jan;51(1):120-122. doi: 10.1177/0049475520967239. Epub 2020 Oct 27.
Visceral leishmaniasis is a tropical parasitic disease caused by the species of the genus The clinical picture includes fever, splenomegaly, leucopenia, anaemia and hypergammaglobulinaemia. There may also be a drop in plasma fibrinogen levels or an increase in plasma fibrinolytic activity. Furthermore, visceral leishmaniasis may be the trigger for secondary haemophagocytic lymphohistiocytosis. On the other hand, disseminated intravascular coagulation may also result. The International Society of Thrombosis and Hemostasis has recommended the use of a scoring system for disseminated intravascular coagulation. An association between visceral leishmaniasis and consumption coagulopathy is not frequent. Our systematic literature review from 1967 to 2019 pointed to the report of only 16 cases. Our case demonstrates that it is necessary to be aware of the existence of this association.
内脏利什曼病是一种热带寄生虫病，由利什曼属的物种引起。临床症状包括发热、脾肿大、白细胞减少、贫血和高γ球蛋白血症。血浆纤维蛋白原水平可能下降，或血浆纤维蛋白溶解活性增加。此外，内脏利什曼病可能引发继发性噬血细胞性淋巴组织细胞增生症。另一方面，也可能导致弥散性血管内凝血。国际血栓与止血学会已推荐使用弥散性血管内凝血评分系统。内脏利什曼病和消耗性凝血病之间的关联并不常见。我们从 1967 年到 2019 年的系统文献回顾仅指出了 16 例报告。我们的病例表明，有必要意识到这种关联的存在。
