Department of Dermatology, Al-Minya University, Al-Minya, Cairo, Egypt.
Department of Dermatology, Faculty of Medicine, Cairo University, Cairo, Egypt.
Indian J Dermatol Venereol Leprol. 2021 Jan-Feb;87(1):22-28. doi: 10.4103/ijdvl.IJDVL_979_19.
Nonsegmental vitiligo is defined as being "often symmetrical", however, no work has tackled the point as to how valid it is to depend upon the concept of symmetricity in generalized nonsegmental vitiligo.
To investigate vitiligo symmetry, taking into account sites of predilection, the clinical characteristics of patients were studied.
This multicentric study included 712 nonsegmental vitiligo patients with 2876 examined lesions. Three models were drawn for each patient. Sagittal, transverse and frontal planes were drawn to divide the body into right/left, upper/lower and anterior/posterior halves respectively. Patients were examined by Wood's light and analyzed for symmetry.
Bilateral involvement was present in 78% (P < 0.001). Studying the similarity of clinical involvement in the upper and lower body parts revealed that such similarity was present in 38%, with a significant positive association in some areas. Studying clinical similarity in the anteroposterior distribution pattern revealed a significant positive association in 11%.
Relatively low number of patients.
We found significant bilateral symmetry in the lesions of 78% of vitiligo patients. Our work could aid in drawing the anticipated vitiligo map in patients with active disease, helping in increasing our understanding of the clinical behaviour of this disease.
非节段性白癜风定义为“常对称”，然而，尚无研究探讨在广义非节段性白癜风中依赖对称性概念的有效性。
考虑好发部位，研究白癜风对称性，研究了患者的临床特征。
本多中心研究纳入了 712 例非节段性白癜风患者，共检查了 2876 处病变。为每位患者绘制了 3 个模型。矢状面、横断面和额状面分别将身体分为右侧/左侧、上部/下部和前侧/后侧。用伍德灯检查患者并分析对称性。
双侧受累占 78%（P<0.001）。研究上下半身临床受累的相似性发现，这种相似性占 38%，在某些区域存在显著的正相关。研究前后分布模式的临床相似性发现，11%存在显著的正相关。
患者数量相对较少。
我们发现 78%的白癜风患者皮损存在显著的双侧对称性。我们的工作可以帮助绘制活动性疾病患者预期的白癜风图谱，有助于增加我们对这种疾病临床行为的理解。
