[CURB-65作为厄瓜多尔COVID-19住院患者30天死亡率的预测指标：COVID-EC研究]
[CURB-65 as a predictor of 30-day mortality in patients hospitalized with COVID-19 in Ecuador: COVID-EC study].
作者信息
Carriel J, Muñoz-Jaramillo R, Bolaños-Ladinez O, Heredia-Villacreses F, Menéndez-Sanchón J, Martin-Delgado J
机构信息
Servicio de Medicina Interna, Hospital Universitario La Zarzuela, Madrid, España.
Instituto de Investigación e Innovación en Salud integral, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil. Guayaquil. Ecuador.
出版信息
Rev Clin Esp. 2022 Jan;222(1):37-41. doi: 10.1016/j.rce.2020.10.001. Epub 2020 Oct 22.
OBJECTIVE
This article aims to assess the utility of CURB-65 in predicting 30-day mortality in adult patients hospitalized with COVID-19.
METHODS
This work is a cohort study conducted between March 1 and April 30, 2020 in Ecuador.
RESULTS
A total of 247 patients were included (mean age 60 ± 14 years, 70% men, overall mortality 41.3%). Patients with CURB-65 ≥ 2 had a higher mortality rate (57 vs. 17%, < .001) that was associated with other markers of risk: advanced age, hypertension, overweight/obesity, kidney failure, hypoxemia, requirement for mechanical ventilation, or onset of respiratory distress.
CONCLUSIONS
CURB-65 ≥ 2 was associated with higher 30-day mortality on the univariate (Kaplan-Meier estimator) and multivariate (Cox regression) analysis.
目的
本文旨在评估CURB-65在预测COVID-19住院成年患者30天死亡率方面的效用。
方法
本研究为队列研究，于2020年3月1日至4月30日在厄瓜多尔进行。
结果
共纳入247例患者（平均年龄60±14岁，70%为男性，总死亡率41.3%）。CURB-65≥2的患者死亡率更高（57%对17%，P<0.001），且与其他风险指标相关：高龄、高血压、超重/肥胖、肾衰竭、低氧血症、机械通气需求或呼吸窘迫发作。
结论
在单变量（Kaplan-Meier估计器）和多变量（Cox回归）分析中，CURB-65≥2与较高的30天死亡率相关。
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