CURB-65 在厄瓜多尔因 COVID-19 住院患者 30 天死亡率预测中的作用：COVID-EC 研究。
CURB-65 as a predictor of 30-day mortality in patients hospitalized with COVID-19 in Ecuador: COVID-EC study.
机构信息
Servicio de Medicina Interna, Hospital Universitario La Zarzuela, Madrid, Spain; Instituto de Investigación e Innovación en Salud integral, Facultad de Ciencias Médicas, Universidad Católica de Santiago de Guayaquil, Guayaquil, Ecuador.
Servicio de Gastroenterología, Hospital IESS Ceibos, Guayaquil, Ecuador.
出版信息
Rev Clin Esp (Barc). 2022 Jan;222(1):37-41. doi: 10.1016/j.rceng.2020.10.006. Epub 2021 Apr 30.
OBJECTIVE
This article aims to assess the utility of CURB-65 in predicting 30-day mortality in adult patients hospitalized with COVID-19.
METHODS
This work is a cohort study conducted between March 1 and April 30, 2020 in Ecuador.
RESULTS
A total of 247 patients were included (mean age 60 ± 14 years, 70% men, overall mortality 41.3%). Patients with CURB-65 ≥ 2 had a higher mortality rate (57 vs. 17%, p < .001) that was associated with other markers of risk: advanced age, hypertension, overweight/obesity, kidney failure, hypoxemia, requirement for mechanical ventilation, or onset of respiratory distress.
CONCLUSIONS
CURB-65 ≥ 2 was associated with higher 30-day mortality on the univariate (Kaplan-Meier estimator) and multivariate (Cox regression) analysis.
目的
本文旨在评估 CURB-65 在预测 COVID-19 成年住院患者 30 天死亡率方面的效用。
方法
这是一项在 2020 年 3 月 1 日至 4 月 30 日期间在厄瓜多尔进行的队列研究。
结果
共纳入 247 例患者（平均年龄 60±14 岁，70%为男性，总死亡率为 41.3%）。CURB-65≥2 的患者死亡率更高（57%比 17%，p<0.001），与其他风险标志物相关：年龄较大、高血压、超重/肥胖、肾衰竭、低氧血症、需要机械通气或出现呼吸窘迫。
结论
CURB-65≥2 在单变量（Kaplan-Meier 估计器）和多变量（Cox 回归）分析中与较高的 30 天死亡率相关。
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