Ozkanli Seyma, Soylemez Tuce, Keskin Havva, Seneldir Hatice, Sahin Fatıma Müberra, Çetinkaya Aysenur, Gokturk Andac, Aycicek Nagihan, Duz Kubra, Cobanoglu Simsek Bengu
Istanbul Medeniyet University, Faculty of Medicine, Department of Pathology, Istanbul, Turkey.
Istanbul Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Istanbul, Turkey.
Medeni Med J. 2020;35(3):219-225. doi: 10.5222/MMJ.2020.92332. Epub 2020 Sep 30.
Our aim in this study is to define the histopathological subtypes, body site distribution, and incidence rates of single or multiple of BCCs. The study is conducted on patients from a single institution in Istanbul which has a migrant-receiving population reflecting that of the country overall.
We retrospectively analyzed data concerning 896 cases of BCC seen between 2014 and 2018. Data about patient demographics (age and sex), tumor diameter,its anatomic localization, histological type, presence of ulceration, lymphovascular/perineural invasion, and single or multiple tumor formations were retrieved from both the hospital's automated system and archived records of the pathology clinic.
Our univariate analysis showed that the patients' age, tumor size, and tumor multicentricity were all significantly related to their gender (p=0.011, p=0.001, and p=0.021, respectively). Further, age, male gender, and tumor size were all significantly related to tumor multicentricity (p=0.003, p=0.021, and p=0.001, respectively). BCC was most commonly found in male, and the diameters of the BCC tumors were also larger in male patients. Multiple BCC was more frequently seen in older and male patients, and the tumors had larger diameters in these groups. The nodular type of BCC was the most frequently seen type in all age groups.
As our study is the first BCC study that has the greatest number of cases in Turkey and as Istanbul reflects the population of Turkey, it is important for the data of BCC cases in Turkey.
本研究旨在明确基底细胞癌（BCC）的组织病理学亚型、身体部位分布以及单发或多发的发病率。该研究针对来自伊斯坦布尔一家单一机构的患者开展，该机构接收的移民人口反映了全国总体情况。
我们回顾性分析了2014年至2018年间896例BCC病例的数据。从医院的自动化系统和病理科的存档记录中获取了有关患者人口统计学信息（年龄和性别）、肿瘤直径、解剖定位、组织学类型、溃疡情况、淋巴管/神经周围侵犯以及肿瘤单发或多发情况的数据。
我们的单因素分析显示，患者的年龄、肿瘤大小和肿瘤多中心性均与性别显著相关（分别为p = 0.011、p = 0.001和p = 0.021）。此外，年龄、男性性别和肿瘤大小均与肿瘤多中心性显著相关（分别为p = 0.003、p = 0.021和p = 0.001）。BCC最常见于男性，男性患者的BCC肿瘤直径也更大。多发BCC在老年男性患者中更常见，且这些组中的肿瘤直径更大。结节型BCC是所有年龄组中最常见的类型。
由于我们的研究是土耳其首例病例数最多的BCC研究，且伊斯坦布尔反映了土耳其的人口情况，因此该研究对于土耳其BCC病例的数据具有重要意义。
