• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

以泪腺肿大为表现的结节病:眼睛不说谎。

Sarcoidosis presenting as lacrimal gland enlargement: Eyes speak the truth.

作者信息

Agarwal Arjit, Chandak Shruti

机构信息

Department of Radiodiagnosis, TMMC and RC, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India.

出版信息

Taiwan J Ophthalmol. 2019 Jun 18;10(3):227-230. doi: 10.4103/tjo.tjo_125_18. eCollection 2020 Jul-Sep.

DOI:10.4103/tjo.tjo_125_18
PMID:33110757
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7585470/
Abstract

Bilateral lacrimal gland enlargement is uncommon; however, its presence induces brainstorming process and intensive discussion between a clinician and an imaging specialist, leading to exploration of multiple systemic disease patterns such as lymphoproliferative disorders, sarcoidosis, Sjögren's syndrome, and tuberculosis. Thoughtful analysis and diagnostic work-up are required to confirm the diagnosis. Sarcoidosis is a rare systemic disease, with ocular involvement being still rarer. Here, we report a case of a young male presenting with nodular swelling over lateral aspects of both the eyes. The imaging study revealed bilateral lacrimal gland enlargement. Further work-up revealed mediastinal and hilar lymphadenopathy with pulmonary nodules which along with biochemical tests lead to the diagnosis of sarcoidosis. The case highlights the ocular symptoms in sarcoidosis and clinicoradiological approach to bilateral lacrimal gland enlargement.

摘要

双侧泪腺肿大并不常见;然而,其出现会引发临床医生和影像专家之间的头脑风暴和深入讨论,从而促使对多种系统性疾病模式进行探索,如淋巴增殖性疾病、结节病、干燥综合征和结核病。需要进行深入分析和诊断检查以确诊。结节病是一种罕见的系统性疾病,眼部受累更为罕见。在此,我们报告一例年轻男性患者,其双眼外侧出现结节状肿胀。影像学检查显示双侧泪腺肿大。进一步检查发现纵隔和肺门淋巴结肿大以及肺部结节,结合生化检查最终诊断为结节病。该病例突出了结节病的眼部症状以及针对双侧泪腺肿大的临床放射学诊断方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/b716cb34035e/TJO-10-227-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/d6727b2c4d71/TJO-10-227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/1ace2f9df146/TJO-10-227-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/d213c9538a9f/TJO-10-227-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/9218493db850/TJO-10-227-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/b716cb34035e/TJO-10-227-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/d6727b2c4d71/TJO-10-227-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/1ace2f9df146/TJO-10-227-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/d213c9538a9f/TJO-10-227-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/9218493db850/TJO-10-227-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b2f/7585470/b716cb34035e/TJO-10-227-g005.jpg

相似文献

1
Sarcoidosis presenting as lacrimal gland enlargement: Eyes speak the truth.以泪腺肿大为表现的结节病:眼睛不说谎。
Taiwan J Ophthalmol. 2019 Jun 18;10(3):227-230. doi: 10.4103/tjo.tjo_125_18. eCollection 2020 Jul-Sep.
2
Bilateral swelling of the lacrimal glands as first manifestation of systemic sarcoidosis in a patient with breast cancer.双侧泪腺肿大作为一名乳腺癌患者系统性结节病的首发表现。
Radiol Case Rep. 2024 May 3;19(8):2988-2991. doi: 10.1016/j.radcr.2024.04.010. eCollection 2024 Aug.
3
Bilaterally Diffuse Lacrimal Gland Involvement: Initial Presentation of Systemic Sarcoidosis.双侧弥漫性泪腺受累:系统性结节病的初始表现
Turk J Ophthalmol. 2017 Jun;47(3):165-168. doi: 10.4274/tjo.89310. Epub 2017 Jun 1.
4
Tattoo-associated lacrimal gland enlargement and sarcoidosis.纹身相关的泪腺肿大与结节病
Am J Ophthalmol Case Rep. 2023 Jul 13;32:101889. doi: 10.1016/j.ajoc.2023.101889. eCollection 2023 Dec.
5
Sarcoidosis presenting as bilateral lacrimal gland swelling: a pediatric case report.双侧泪腺肿胀为表现的结节病:一例儿科病例报告。
Pediatr Rheumatol Online J. 2021 Aug 6;19(1):117. doi: 10.1186/s12969-021-00606-1.
6
Bilateral Dacryoadenitis As the First Presentation in an Undiagnosed Sarcoidosis Patient.双侧泪腺炎作为未确诊结节病患者的首发表现
Cureus. 2023 Nov 5;15(11):e48287. doi: 10.7759/cureus.48287. eCollection 2023 Nov.
7
The frequency of granulomatous lacrimal gland inflammation as a cause of lacrimal gland enlargement in patients without a diagnosis of systemic sarcoidosis.在未诊断为系统性结节病的患者中,肉芽肿性泪腺炎作为泪腺肿大原因的发生率。
Orbit. 2013 Jun;32(3):151-5. doi: 10.3109/01676830.2013.771676. Epub 2013 Mar 12.
8
Sarcoidosis presenting as Wallenberg syndrome and panuveitis.以瓦伦贝格综合征和全葡萄膜炎为表现的结节病。
Respir Med Case Rep. 2018 Mar 3;24:16-18. doi: 10.1016/j.rmcr.2018.03.002. eCollection 2018.
9
[Lacrimal gland hypertrophy: revealing sarcoidosis].[泪腺肥大:揭示结节病]
J Fr Ophtalmol. 1999 Jun-Jul;22(6):666-70.
10
Multiple bilateral pulmonary nodules masquerading as pulmonary metastasis; a case of nodular sarcoidosis.多发性双侧肺结节伪装成肺转移瘤;结节病一例
Electron Physician. 2016 Aug 25;8(8):2802-2806. doi: 10.19082/2802. eCollection 2016 Aug.

引用本文的文献

1
Bilateral swelling of the lacrimal glands as first manifestation of systemic sarcoidosis in a patient with breast cancer.双侧泪腺肿大作为一名乳腺癌患者系统性结节病的首发表现。
Radiol Case Rep. 2024 May 3;19(8):2988-2991. doi: 10.1016/j.radcr.2024.04.010. eCollection 2024 Aug.
2
Tattoo-associated lacrimal gland enlargement and sarcoidosis.纹身相关的泪腺肿大与结节病
Am J Ophthalmol Case Rep. 2023 Jul 13;32:101889. doi: 10.1016/j.ajoc.2023.101889. eCollection 2023 Dec.
3
Sarcoidosis of the lacrimal gland: the prominence of the differential diagnosis.

本文引用的文献

1
Immunoglobulin G4-related ophthalmic disease.免疫球蛋白G4相关性眼病
Taiwan J Ophthalmol. 2018 Jan-Mar;8(1):9-14. doi: 10.4103/tjo.tjo_12_17.
2
Ocular Sarcoidosis.眼部结节病
Clin Chest Med. 2015 Dec;36(4):669-83. doi: 10.1016/j.ccm.2015.08.009.
3
Sarcoidosis in tuberculosis-endemic regions: India.结核病流行地区的结节病:印度
泪腺结节病:鉴别诊断的突出表现。
BMJ Case Rep. 2023 May 23;16(5):e253880. doi: 10.1136/bcr-2022-253880.
J Ophthalmic Inflamm Infect. 2013 Jun 27;3(1):53. doi: 10.1186/1869-5760-3-53.
4
Pulmonary sarcoidosis: typical and atypical manifestations at high-resolution CT with pathologic correlation.肺部肉样瘤病:高分辨率 CT 的典型和非典型表现及与病理学的相关性。
Radiographics. 2010 Oct;30(6):1567-86. doi: 10.1148/rg.306105512.
5
Lacrimal fossa lesions: pictorial review of CT and MRI features.泪腺窝病变:CT与MRI特征的影像综述
Orbit. 2008;27(6):410-8. doi: 10.1080/01676830802333667.
6
Imaging features of ocular adnexal lymphoproliferative disease.眼附属器淋巴增殖性疾病的影像学特征。
Eye (Lond). 2006 Oct;20(10):1189-95. doi: 10.1038/sj.eye.6702382.
7
Tubercular dacryoadenitis--a case report and review of literature.结核性泪腺炎——病例报告及文献综述
Indian J Pathol Microbiol. 2006 Jul;49(3):385-7.
8
Lymphoproliferative lesions of the lacrimal gland: clinicopathological, immunohistochemical and molecular genetic analysis.泪腺的淋巴增生性病变:临床病理、免疫组织化学及分子遗传学分析
Can J Ophthalmol. 2005 Apr;40(2):151-60. doi: 10.1016/S0008-4182(05)80026-2.
9
Update of ocular manifestations in sarcoidosis.
Sarcoidosis Vasc Diffuse Lung Dis. 2002 Oct;19(3):167-75.
10
Sarcoidosis.结节病
N Engl J Med. 1997 Apr 24;336(17):1224-34. doi: 10.1056/NEJM199704243361706.