Jafari Mostafa, Farrokh Donya, Mohammadpanah Najmeh
MD, Department of Internal Medicine, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
MD, Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Electron Physician. 2016 Aug 25;8(8):2802-2806. doi: 10.19082/2802. eCollection 2016 Aug.
Sarcoidosis is a multi-system inflammatory disorder of unknown etiology that is manifested by the presence of non-caseating granulomas. Multiple pulmonary nodules are rare presentations of sarcoidosis. We report a case of nodular sarcoidosis in a young male of Middle-East origin who had initially presented with bilateral painful ankle edema. His chest X-ray showed multiple bilateral pulmonary nodules. A high resolution computed tomography scan of the chest demonstrated multiple pulmonary nodular lesions and also mediastinal and hilar lymphadenopathy. Subsequent biopsies revealed non-necrotizing granuloma with multi-nucleated giant cells indicative of sarcoidosis. An appropriate work-up was done to confirm the true nature of the nodules and facilitate treatment.
结节病是一种病因不明的多系统炎症性疾病，表现为非干酪样肉芽肿的存在。多发性肺结节是结节病的罕见表现。我们报告一例中东裔年轻男性的结节性结节病病例，该患者最初表现为双侧踝关节疼痛性水肿。他的胸部X线显示双侧多个肺结节。胸部高分辨率计算机断层扫描显示多个肺结节性病变以及纵隔和肺门淋巴结肿大。随后的活检显示非坏死性肉芽肿伴有多核巨细胞，提示结节病。进行了适当的检查以确认结节的真实性质并促进治疗。
