Department of Gastrointestinal Oncology, Moffitt Cancer Center, 12902 Magnolia Dr., Tampa, FL, 33612, USA.
Department of Radiology, Moffitt Cancer Center, Tampa, FL, USA.
Abdom Radiol (NY). 2021 May;46(5):1783-1804. doi: 10.1007/s00261-020-02827-6. Epub 2020 Oct 28.
A nonoperative management strategy, or Watch-and-Wait, following neoadjuvant therapies of locally advanced rectal adenocarcinoma is increasingly considered for select patients. Yet, standardized tumor response assessment to best select and surveil suitable patients remains an unmet clinical challenge. Endoscopic and MRI currently provide the most reliable tumor response estimations. However, resources illustrating variable tumor responses to neoadjuvant therapies remain limited. This pictorial review aims to provide detailed and annotated examples of common endoscopic and MRI findings of rectal cancer treatment response, while also emphasizing their respective diagnostic shortcomings and consequently, the necessity for a multidisciplinary approach to optimally manage these patients.
局部晚期直肠腺癌新辅助治疗后，越来越多的患者选择非手术治疗策略，即“观察等待”。然而，为了最佳选择和监测合适的患者，标准化的肿瘤反应评估仍然是一个未满足的临床挑战。内镜和 MRI 目前提供了最可靠的肿瘤反应估计。然而，描述肿瘤对新辅助治疗反应的变化的资源仍然有限。本影像学综述旨在提供直肠肿瘤治疗反应的常见内镜和 MRI 表现的详细和注释示例，同时强调它们各自的诊断缺陷，因此需要多学科方法来优化这些患者的管理。
