CUNY Institute for Implementation Science in Population Health, New York, New York.
CUNY Graduate School of Public Health and Health Policy, New York, New York.
AIDS Educ Prev. 2020 Oct;32(5):367-377. doi: 10.1521/aeap.2020.32.5.367.
Despite proven effectiveness in reducing HIV transmission, pre-exposure prophylaxis (PrEP) use remains low among those who meet the recommended CDC guidance for PrEP use. Data are from a U.S. national cohort of men and trans persons who have sex with men (2017-2018). Logistic regression analyses were used to determine individual and partner factors associated with intentions to use PrEP among non-PrEP-using participants reporting a main partner ( = 1,671). Prior PrEP use among participants (14.2%) and their partners (7.7%) was low. Participants' prior PrEP use and main partner's HIV-positive status were both positively associated with intentions to use PrEP. HIV prevention interventions incorporating main partners may be effective in increasing PrEP use.
尽管暴露前预防(PrEP)在降低 HIV 传播方面已被证实有效,但符合美国疾病控制与预防中心(CDC)推荐的 PrEP 使用指南的人群中,PrEP 的使用率仍然较低。该数据来自于美国一项针对男男性行为者和跨性别者的全国队列研究(2017-2018 年)。采用逻辑回归分析方法,确定了与未使用 PrEP 且报告有主要性伴侣的参与者(n=1671)使用 PrEP 意向相关的个体和伴侣因素。参与者(14.2%)及其伴侣(7.7%)中 PrEP 的既往使用率较低。参与者的既往 PrEP 使用和主要伴侣的 HIV 阳性状态均与使用 PrEP 的意向呈正相关。将主要性伴侣纳入 HIV 预防干预措施可能会有效提高 PrEP 的使用率。