MacFadyen D J, Schneider R J, Chisholm I A
Department of Clinical Neurological Sciences, University Hospital, Saskatoon, Saskatchewan, Canada.
Can J Neurol Sci. 1987 Aug;14(3):315-8. doi: 10.1017/s0317167100026706.
We report the seventh case of a self-limiting syndrome of brain, inner ear and retinal microangiopathy which affects adult women producing mild to moderate mental status and personality changes, mild pyramidal and cerebellar dysfunction, patchy and asymmetrical visual loss secondary to non-inflammatory retinal infarctions, and asymmetrical neurosensory hearing loss. There is no clinical or laboratory evidence of involvement beyond the brain, the eyes and the ears. Magnetic resonance imaging or brain biopsy in previously reported cases best outline the brain pathology: multiple microinfarcts. All cases have been treated with steroids or cyclophosphamide. The etiology is unknown but may be related to systemic lupus erythematosus.
我们报告了第七例脑、内耳和视网膜微血管病变的自限性综合征病例，该综合征影响成年女性，可导致轻度至中度精神状态和人格改变、轻度锥体束和小脑功能障碍、非炎性视网膜梗死继发的斑片状和不对称性视力丧失以及不对称性神经性听力损失。没有临床或实验室证据表明病变累及脑、眼和耳以外的部位。先前报道病例的磁共振成像或脑活检最能清晰显示脑部病理情况：多发性微梗死。所有病例均接受了类固醇或环磷酰胺治疗。病因不明，但可能与系统性红斑狼疮有关。
