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口服抗凝剂治疗的心房颤动卒中患者:第戎人群卒中登记处与法国国家健康数据库的比较。

Stroke Patients with Atrial Fibrillation Treated with Oral Anticoagulants: Comparison of the Population-Based Stroke Registry of Dijon and the French National Health Databases.

机构信息

Non-Communicable Diseases Department, Santé Publique France, Saint-Maurice, France,

Non-Communicable Diseases Department, Santé Publique France, Saint-Maurice, France.

出版信息

Neuroepidemiology. 2020;54(6):506-512. doi: 10.1159/000511206. Epub 2020 Oct 28.

Abstract

INTRODUCTION

The objective of this study was to evaluate the complementarity of the French national health database (Système national des données de Santé, SNDS) and the Dijon Stroke Registry for the epidemiology of stroke patients with anticoagulated atrial fibrillation (AF).

METHODS

The SNDS collects healthcare prescriptions and procedures reimbursed by the French national health insurance for almost all of the 66 million individuals living in France. A previously published algorithm was used to identify AF newly treated with oral anticoagulants. The Dijon Stroke Registry is a population-based study covering the residents of the city of Dijon since 1985 and records all stroke cases of the area. We compared the proportions of stroke patients with anticoagulated AF in the city of Dijon identified in SNDS databases to those registered in the Dijon Stroke Registry.

RESULTS

For the period 2013-2017 in the city of Dijon, 1,146 strokes were identified in the SNDS and 1,188 in the registry. The proportion of strokes with anticoagulated AF was 13.4% in the SNDS and 20.3% in the Dijon Stroke Registry. Very similar characteristics were found between patients identified through the 2 databases. The overall prevalence of AF in stroke patients could be estimated only in the Dijon stroke registry and was 30.4% for the study period.

DISCUSSION/CONCLUSION: If administrative health databases can be a useful tool to study the epidemiology of anticoagulated AF in stroke patients, population-based stroke registries as the Dijon Stroke Registry remain essential to fully study the epidemiology of strokes with anticoagulated AF.

摘要

简介

本研究的目的是评估法国国家健康数据库(Système national des données de Santé,SNDS)和第戎卒中登记处(Dijon Stroke Registry)在抗凝治疗的心房颤动(AF)卒中患者流行病学中的互补性。

方法

SNDS 收集了法国全国医疗保险为近 6600 万法国人支付的医疗保健处方和程序。使用之前发表的算法来识别新接受口服抗凝剂治疗的 AF。第戎卒中登记处是一项基于人群的研究,涵盖了自 1985 年以来第戎市的居民,并记录了该地区所有的卒中病例。我们比较了 SNDS 数据库中发现的抗凝治疗 AF 的卒中患者比例与第戎卒中登记处记录的比例。

结果

在 2013 年至 2017 年期间,SNDS 中发现了 1146 例卒中,登记处中发现了 1188 例。SNDS 中有抗凝 AF 的卒中比例为 13.4%,而第戎卒中登记处为 20.3%。通过这两个数据库发现的患者具有非常相似的特征。研究期间,只有在第戎卒中登记处才能估计卒中患者 AF 的总体患病率,为 30.4%。

讨论/结论:如果行政健康数据库可以成为研究抗凝治疗 AF 卒中患者流行病学的有用工具,那么基于人群的卒中登记处,如第戎卒中登记处,对于全面研究抗凝治疗 AF 的卒中流行病学仍然至关重要。

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