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妊娠患者的大麻素呕吐综合征:临床病例及文献综述

Cannabinoid hyperemesis syndrome in the pregnant patient: clinical case and literature review.

作者信息

Flament Julien, Scius Nathan, Thonon Henri

机构信息

Emergency Department, CHU UCL Namur, 1, rue Dr G. Therasse, 5530 Mont-Godinne, Yvoir, Belgium.

出版信息

Int J Emerg Med. 2020 Oct 28;13(1):52. doi: 10.1186/s12245-020-00311-y.

Abstract

BACKGROUND

Cannabis use is on the rise. Several cases of cannabinoid hyperemesis syndrome, secondary to chronic cannabis intoxication, have been described worldwide, but few cases have described this entity in pregnant women.

CASE PRESENTATION

We describe a 29-year-old pregnant patient that had consumed cannabis and experienced uncontrolled vomiting. The use of hot baths, the rapid improvement in symptoms, and results of complementary examinations suggested a diagnosis of cannabinoid hyperemesis syndrome. The patient could return home, and she continued her pregnancy and childbirth without peculiarities.

CONCLUSION

Cannabinoid hyperemesis syndrome should be considered in the differential diagnosis of vomiting in pregnancy. Consumption of cannabis must be systematically included in the anamnesis. However, it seems to be somewhat unacceptable socially or medically. Consumption must be stopped to manage symptoms.

摘要

背景

大麻的使用呈上升趋势。全球已报道了几例继发于慢性大麻中毒的大麻素呕吐综合征病例,但很少有病例描述孕妇中的这一病症。

病例报告

我们描述了一名29岁的孕妇,她吸食了大麻并出现无法控制的呕吐。洗热水澡、症状迅速改善以及辅助检查结果提示诊断为大麻素呕吐综合征。患者可以回家,她继续妊娠并顺利分娩,无特殊情况。

结论

在妊娠呕吐的鉴别诊断中应考虑大麻素呕吐综合征。在问诊时必须系统地询问是否吸食过大麻。然而,这在社会或医学上似乎有些难以接受。必须停止吸食以控制症状。

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本文引用的文献

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Nausea and vomiting of pregnancy and hyperemesis gravidarum.妊娠恶心和呕吐及妊娠剧吐。
Nat Rev Dis Primers. 2019 Sep 12;5(1):62. doi: 10.1038/s41572-019-0110-3.
3
Recurrent Nausea and Vomiting in a Pregnant Woman with Chronic Marijuana Use.一名长期使用大麻的孕妇出现反复恶心和呕吐
Case Rep Obstet Gynecol. 2018 Sep 16;2018:9746062. doi: 10.1155/2018/9746062. eCollection 2018.
4
Cannabinoid Hyperemesis Syndrome: Reports of Fatal Cases.大麻素呕吐综合征:致命病例报告。
J Forensic Sci. 2019 Jan;64(1):270-274. doi: 10.1111/1556-4029.13819. Epub 2018 May 16.
8
[Cannabinoid hyperemesis syndrome: A review of the literature].[大麻素呕吐综合征:文献综述]
Arch Pediatr. 2016 Jun;23(6):619-23. doi: 10.1016/j.arcped.2016.01.016. Epub 2016 Apr 12.

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