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大麻素呕吐综合征:一种被低估的导致妊娠恶心和呕吐的实体。

Cannabinoid hyperemesis syndrome: an underreported entity causing nausea and vomiting of pregnancy.

机构信息

Department of Gynecology and Obstetrics, University Hospital Basel (UHB), Spitalstrasse 21, 4031 Basel, Switzerland.

出版信息

Arch Gynecol Obstet. 2011 Nov;284(5):1095-7. doi: 10.1007/s00404-010-1811-8. Epub 2010 Dec 18.

DOI:10.1007/s00404-010-1811-8
PMID:21170540
Abstract

INTRODUCTION

In the western world, cannabis is the most widely used drug of abuse. Cannabinoid hyperemesis syndrome, which seems to be a rare paradoxical reaction in individuals with a particular predisposition, is characterized by cyclic severe nausea and vomiting in long-term cannabis users. While the symptoms are unresponsive to antiemetic drugs, compulsive hot baths result in a considerable symptom relief.

METHODS

We report the first case of cannabinoid hyperemesis syndrome in pregnancy. A 26-year-old patient was admitted to our clinic in the 10th week of gestation.

CONCLUSION

Before undertaking time-consuming and expensive medical examinations to rule out other medical reasons for therapy-resistant hyperemesis in pregnancy, obstetricians should determine whether compulsive bathing or showering provides symptomatic relief and ask specific questions regarding possible/suspected cannabis consumption.

摘要

简介

在西方世界,大麻是最广泛使用的滥用药物。大麻素呕吐综合征似乎是一种在具有特定易感性的个体中罕见的矛盾反应,其特征是长期大麻使用者出现周期性严重恶心和呕吐。虽然这些症状对止吐药物没有反应,但强制性洗热水澡会导致症状明显缓解。

方法

我们报告了首例妊娠大麻素呕吐综合征病例。一名 26 岁患者在妊娠 10 周时被收入我院。

结论

在进行耗时且昂贵的医学检查以排除妊娠治疗抵抗性呕吐的其他医学原因之前,产科医生应确定强制性沐浴或淋浴是否能提供症状缓解,并询问有关可能/疑似大麻使用的具体问题。

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Arch Gynecol Obstet. 2011 Nov;284(5):1095-7. doi: 10.1007/s00404-010-1811-8. Epub 2010 Dec 18.
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