Clinic for Swine, Small Ruminants, Forensic Medicine and Ambulatory Service, University of Veterinary Medicine Hannover, Bischofsholer Damm 15, 30173, Hannover, Germany.
Institute for Pathology, University of Veterinary Medicine Hannover, Hannover, Germany.
BMC Vet Res. 2020 Oct 28;16(1):406. doi: 10.1186/s12917-020-02615-w.
Calcinosis has been reported for a broad range of different animals. Causes for calcinosis include metabolic disorders due to kidney failure, intoxication with calcinogenic plants, or iatrogenic overdose of vitamin D. Especially young animals seem to be very susceptible to developing calcinosis. Currently, however, there is a lack of information on calcinosis in wildlife.
The following case report describes a roe deer fawn admitted to a clinic due to general weakness and myiasis. Plasma levels for creatinine, urea and phosphate were highly elevated, whereas the total calcium level was decreased. Necropsy revealed calcinosis due to calcification in many organs. The reason for calcinosis in this particular case might be kidney failure. Plasma samples from other hunted roe deer fawns also showed high phosphate levels.
Roe deer fawns might be susceptible to calcinosis due to high plasma phosphate, which could be a result of kidney failure or different feed. Further research into calcium and phosphate homeostasis in roe deer is necessary.
钙沉积在广泛的不同动物中均有报道。钙沉积的原因包括肾衰竭引起的代谢紊乱、摄入具有成钙作用的植物或维生素 D 治疗性过量。特别是幼小动物似乎非常容易发生钙沉积。然而，目前关于野生动物钙沉积的信息还很缺乏。
本病例报告描述了一只因全身虚弱和蝇蛆病而被送诊的狍鹿幼崽。其肌酐、尿素和磷酸盐的血浆水平显著升高，而总钙水平降低。尸检显示，由于许多器官的钙化而发生钙沉积。在这种特殊情况下，钙沉积的原因可能是肾衰竭。从其他被猎捕的狍鹿幼崽采集的血浆样本也显示出高磷酸盐水平。
狍鹿幼崽可能由于高磷酸盐血症而容易发生钙沉积，这可能是肾衰竭或不同饲料的结果。需要进一步研究狍鹿的钙和磷酸盐体内平衡。
