Department of Gastroenterology, Toranomon Hospital, Japan.
Department of Gastroenterology Surgery, Toranomon Hospital, Japan.
Intern Med. 2021 Apr 1;60(7):1005-1009. doi: 10.2169/internalmedicine.6015-20. Epub 2020 Oct 28.
Mucosal prolapse syndrome (MPS) is a benign inflammatory disease of the rectum that causes symptoms such as blood-stained stools and anemia. However, there is no treatment with a proven long-term efficacy for MPS. A 53-year-old man presented with blood-stained stools and anemia due to MPS and was treated conservatively for 1 year. However, his symptoms did not improve. We performed endoscopic submucosal dissection (ESD) for MPS. He has had no symptoms for six years after ESD, and the recurrence of MPS was not seen on endoscopy. This case shows that ESD can be effective for the long-term treatment of symptomatic MPS.
黏膜脱垂综合征（Mucosal prolapse syndrome，MPS）是一种良性直肠炎症性疾病，可引起血便和贫血等症状。然而，目前尚无针对 MPS 的经证实具有长期疗效的治疗方法。一位 53 岁男性因 MPS 出现血便和贫血，并接受了 1 年的保守治疗。但他的症状并未改善。我们对 MPS 进行了内镜黏膜下剥离术（endoscopic submucosal dissection，ESD）。ESD 后 6 年，他没有出现任何症状，内镜也未发现 MPS 复发。该病例表明，ESD 可有效治疗有症状的 MPS，且疗效持久。
