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孟加拉国新冠肺炎患者的胃肠道表现:一项横断面研究

Gastrointestinal Manifestations among COVID-19 Patients in Bangladesh: A Cross Sectional Study.

作者信息

Khalil M M, Gain G, Mahbub-Uz-Zaman K, Karim M E, Sarker K D, Akter D, Patwary M I, Chowdhury M R, Arefin M K, Ahmed F

机构信息

Dr Md. Musab Khalil, Assistant Registrar, Department of Medical Gastroenterology, Sheikh Russel National Gastroliver Institute and Hospital (SRNGI&H), Mohakhali, Dhaka, Bangladesh; E-mail:

出版信息

Mymensingh Med J. 2020 Oct;29(4):956-963.

Abstract

This study was done to find out the frequency of gastrointestinal manifestations among adult COVID-19 patients in Bangladesh. This descriptive cross sectional retrospective study was conducted from 27 May till 20 June 2020. Data were collected retrospectively from three different hospitals of Dhaka, Bangladesh. Patients were interviewed over telephone and verbal consents were taken. Their demographic and clinical profiles were put in the questionnaires by the investigators themselves. Statistical analysis was done thereafter. Out of 226 patients diagnosed with COVID-19, 145(61.4%) patients had gastrointestinal symptoms. Five of them had none other than gastrointestinal symptoms. Twenty six patients were asymptomatic. Mean age of the patients with were 41.6±14.8 years. Males were affected almost equally as the females (51.72% vs. 48.27%) (Ratio 1.1:1). Anorexia (44.7%) followed by diarrhoea (35%) and nausea (22.6%) were the predominant symptoms. Patients with co-morbidities (74.7%) were more prone to develop GI symptoms. Family members (71.6%) of COVID-19 patients with GI symptomatic patients were more affected than the others. Hospitalizations (77.6%) were more among GI symptomatic patients than the others. Thirty Five percent (35%) patients had diarrhoea. Mean duration of diarrhoea was 2.7±1.7 days with a frequency of were 4±1.8 days per day. Gastrointestinal manifestations are common among patients with COVID-19. Clinicians need to be aware of the GI features amongst COVID-19 patients so that they can be addressed and treated effectively and immediately. Further large scale study is needed to predict the disease outcome among COVID 19 patients with GI symptoms.

摘要

本研究旨在查明孟加拉国成年新冠肺炎患者胃肠道表现的发生率。这项描述性横断面回顾性研究于2020年5月27日至6月20日进行。数据从孟加拉国达卡的三家不同医院回顾性收集。通过电话对患者进行访谈并获得口头同意。研究人员自己将患者的人口统计学和临床资料填入问卷。此后进行统计分析。在226例确诊为新冠肺炎的患者中,145例(61.4%)有胃肠道症状。其中5例仅有胃肠道症状。26例患者无症状。有胃肠道症状患者的平均年龄为41.6±14.8岁。男性和女性受影响程度几乎相同(51.72%对48.27%)(比例为1.1:1)。主要症状依次为厌食(44.7%)、腹泻(35%)和恶心(22.6%)。有合并症的患者(74.7%)更容易出现胃肠道症状。有胃肠道症状的新冠肺炎患者的家庭成员(71.6%)比其他人受影响更大。有胃肠道症状的患者住院率(77.6%)高于其他人。35%的患者有腹泻。腹泻的平均持续时间为2.7±1.7天,每天排便次数为4±1.8次。胃肠道表现在新冠肺炎患者中很常见。临床医生需要了解新冠肺炎患者的胃肠道特征,以便能够有效且及时地对其进行处理和治疗。需要进一步开展大规模研究以预测有胃肠道症状的新冠肺炎患者的疾病转归。

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