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现实生活人群中钕钇铝石榴石激光晶状体囊切开术发生率的评估

Evaluation of Nd:YAG Laser Capsulotomy Rates in a Real-Life Population.

作者信息

Ling Roland, Borkenstein Eva-Maria, Borkenstein Andreas F

机构信息

The Medical Eye Clinic, Royal Devon and Exeter Hospital, Exeter, UK.

Privatklinik der Kreuzschwestern Graz, Private Practice Borkenstein & Borkenstein, Graz, Austria.

出版信息

Clin Ophthalmol. 2020 Oct 13;14:3249-3257. doi: 10.2147/OPTH.S276329. eCollection 2020.

Abstract

OBJECTIVE

The objective of this study was to assess the rate of posterior capsule opacification (PCO), under "real-life" conditions, as measured by rates of Nd:YAG laser intervention, rather than from a controlled study from which patients with conditions predisposing to PCO have been excluded.

METHODS AND ANALYSIS

This was a retrospective, multicenter study in an unselected consecutive cohort of patients undergoing surgery for senile cataract. Patients aged 18 years and older, previously implanted with the CT LUCIA 611P IOL, were contacted at 12, 18 and 24 months to ascertain if they had received Nd:YAG laser treatment. There was an additional assessment at 36 months at the Austrian centre.

RESULTS

A total of 200 patients were recruited at two centers. Laser capsulotomy rates were 4.5% at 1 year and 10% by year 2 and 12% by year 3. Three Nd:YAG capsulotomies, carried out at other external centers, were performed for reasons other than PCO, including astigmatism, epiretinal membrane and ARMD. If these patients are excluded, the true rate of Nd:YAG carried out for PCO at 1 year was 3.5% and at 2 years was 8.5%.

CONCLUSION

It is critical to ensure that Nd:YAG capsulotomies are being performed only for the correct clinical reason. Carrying out unnecessary procedures places the patient at risk of adverse events, is a cost to the healthcare system, and is likely to have no direct visual benefit for the patient. In PCO studies, it should be a requirement to document the fibrosis grade to confirm that Nd:YAG capsulotomy was correctly indicated.

摘要

目的

本研究的目的是在“现实生活”条件下,通过钕:钇铝石榴石激光干预率来评估后囊膜混浊(PCO)的发生率,而非来自排除了易患PCO病症患者的对照研究。

方法与分析

这是一项针对接受老年性白内障手术的未筛选连续队列患者的回顾性多中心研究。对年龄在18岁及以上、先前植入CT LUCIA 611P人工晶状体的患者,在12、18和24个月时进行随访,以确定他们是否接受了钕:钇铝石榴石激光治疗。奥地利中心在36个月时进行了额外评估。

结果

两个中心共招募了200名患者。1年时激光囊膜切开率为4.5%,2年时为10%,3年时为12%。在其他外部中心进行的3次钕:钇铝石榴石囊膜切开术,其原因并非PCO,包括散光、视网膜前膜和年龄相关性黄斑变性。如果排除这些患者,1年时因PCO进行钕:钇铝石榴石激光治疗的实际发生率为3.5%,2年时为8.5%。

结论

确保仅出于正确的临床原因进行钕:钇铝石榴石囊膜切开术至关重要。进行不必要的手术会使患者面临不良事件风险,给医疗系统带来成本,且可能对患者没有直接的视力益处。在PCO研究中,应要求记录纤维化程度,以确认钕:钇铝石榴石囊膜切开术的指征是否正确。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f079/7569058/2f045ed321e5/OPTH-14-3249-g0001.jpg

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