人体丝虫病中特异性体液免疫反应的评估。
Evaluation of specific humoral immune responses in human filariasis.
作者信息
Kumar H, Malhotra A, Santhanam S, Jain D C, Ghosh T K
机构信息
Immunology Laboratory, National Institute of Communicable Diseases, Delhi.
出版信息
Folia Parasitol (Praha). 1987;34(3):249-54.
Using the antigens prepared from adult worms of B. malayi and D. immitis, a total of 37 malayan and 150 bancroftian serum samples were analysed for the presence of filarial specific antibodies by counterimmunoelectrophoresis and indirect enzyme linked immunosorbent assay. It was observed that microfilaraemic cases do show good specific humoral immune responses against homologous as well as heterologous antigen. Of the two antigens used, B. malayi adult antigen was found to be superior to D. immitis antigen in the detection of filarial antibodies.
利用从马来布鲁线虫和犬恶丝虫成虫制备的抗原，通过对流免疫电泳和间接酶联免疫吸附测定，对总共37份马来丝虫病血清样本和150份班氏丝虫病血清样本进行了丝虫特异性抗体检测。结果发现，微丝蚴血症病例确实对同源和异源抗原都表现出良好的特异性体液免疫反应。在所使用的两种抗原中，发现马来布鲁线虫成虫抗原在检测丝虫抗体方面优于犬恶丝虫抗原。
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