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Differentiating the effect of antipsychotic medication and illness on brain volume reductions in first-episode psychosis: A Longitudinal, Randomised, Triple-blind, Placebo-controlled MRI Study.首发精神病患者抗精神病药物和疾病对脑容量减少影响的鉴别：一项纵向、随机、三盲、安慰剂对照 MRI 研究。
Neuropsychopharmacology. 2021 Jul;46(8):1494-1501. doi: 10.1038/s41386-021-00980-0. Epub 2021 Feb 26.
2
Do Unremitted Psychotic Symptoms Have an Effect on the Brain? A 2-Year Follow-up Imaging Study in First-Episode Psychosis.持续存在的精神病症状会对大脑产生影响吗？一项针对首发精神病的2年随访影像学研究。
Schizophr Bull Open. 2020 Jan;1(1):sgaa039. doi: 10.1093/schizbullopen/sgaa039. Epub 2020 Aug 24.
3
Individual deviations from normative models of brain structure in a large cross-sectional schizophrenia cohort.大样本横断面精神分裂症队列中脑结构偏离正常模式的个体差异。
Mol Psychiatry. 2021 Jul;26(7):3512-3523. doi: 10.1038/s41380-020-00882-5. Epub 2020 Sep 22.
4
Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders.6 种精神障碍的皮质厚度虚拟组织学和共同神经生物学
JAMA Psychiatry. 2021 Jan 1;78(1):47-63. doi: 10.1001/jamapsychiatry.2020.2694.
5
Contributions of modern network science to the cognitive sciences: revisiting research spirals of representation and process.现代网络科学对认知科学的贡献：重新审视表征与过程的研究螺旋
Proc Math Phys Eng Sci. 2020 Jun;476(2238):20190825. doi: 10.1098/rspa.2019.0825. Epub 2020 Jun 10.
6
Finding specificity in structural brain alterations through Bayesian reverse inference.通过贝叶斯逆推断寻找结构脑改变的特异性。
Hum Brain Mapp. 2020 Oct 15;41(15):4155-4172. doi: 10.1002/hbm.25105. Epub 2020 Aug 23.
7
Plasticity and Spontaneous Activity Pulses in Disused Human Brain Circuits.失用人类大脑回路中的可塑性和自发性活动脉冲。
Neuron. 2020 Aug 5;107(3):580-589.e6. doi: 10.1016/j.neuron.2020.05.007. Epub 2020 Jun 16.
8
A meta-analytic approach to mapping co-occurrent grey matter volume increases and decreases in psychiatric disorders.一种用于绘制精神疾病中同时出现的灰质体积增加和减少情况的荟萃分析方法。
Neuroimage. 2020 Nov 15;222:117220. doi: 10.1016/j.neuroimage.2020.117220. Epub 2020 Aug 8.
9
Gray Matter Changes in the Insular Cortex During the Course of the Schizophrenia Spectrum.精神分裂症谱系病程中脑岛皮质的灰质变化
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Am J Psychiatry. 2020 Aug 1;177(8):671-685. doi: 10.1176/appi.ajp.2020.20060845.

Reconsidering brain tissue changes as a mechanistic focus for early intervention in psychiatry.

作者信息

Palaniyappan Lena, Sukumar Niron

机构信息

From the Robarts Research Institute, Western University (Palaniyappan); the Department of Psychiatry, Western University (Palaniyappan, Sukumar); the Lawson Health Research Institute, Imaging Division (Palaniyappan); and the Department of Medical Biophysics, Western University (Palaniyappan), London, Ont., Canada.

出版信息

J Psychiatry Neurosci. 2020 Nov;44(6):373-378. doi: 10.1503/jpn.200172.

DOI:10.1503/jpn.200172
PMID:33119489
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7595740/
Abstract
摘要