Hegedüs L, Rasmussen N, Knudsen N
Department of Internal Medicine and Endocrinology F, Herlev Hospital, University of Copenhagen, Denmark.
Horm Metab Res. 1987 Aug;19(8):391-2. doi: 10.1055/s-2007-1011833.
Thyroid volume, measured ultrasonically, and serum levels of T4, T3 and TSH were determined every season during one year in 13 healthy males. A mean variation in thyroid volume of approximately 23% between minimum values (15.8 +/- 1.7 ml, summer) and maximum values (19.5 +/- 1.9 ml, winter) was found (P less than 0.01), although no significant differences in the other thyroid variables could be demonstrated. This seasonal variation in thyroid size should be taken into account when goitre frequency, goitrogenic action of drugs, and goitre treatment effects are evaluated.
在一年中，对13名健康男性每一个季节都进行超声测量甲状腺体积，并测定血清T4、T3和TSH水平。发现甲状腺体积的最小值（夏季，15.8±1.7毫升）和最大值（冬季，19.5±1.9毫升）之间平均变化约为23%（P<0.01），尽管其他甲状腺变量无显著差异。在评估甲状腺肿发生率、药物的致甲状腺肿作用以及甲状腺肿治疗效果时，应考虑甲状腺大小的这种季节性变化。
