Pherwani A V, Desai A G
Institute of Child Health, J. J. Group of Government Hospitals, Bombay.
Indian J Physiol Pharmacol. 1987 Jan-Mar;31(1):58-62.
An open trial of Ketotifen was conducted on 29 children suffering from asthma of varying duration. The drug was given orally in a dose of 1 mg twice a day. Children were followed up weekly for a period of 3 months. It was found beneficial (though the benefit was not statistically significant) in children having asthma of less than 2 years duration who were taking one drug regularly or were on occasional treatment. There was marginal effect in children taking salbutamol and theophylline together, but irregularly and no benefit in children taking prednisolone.
对29名患有不同病程哮喘的儿童进行了酮替芬的开放试验。药物口服，剂量为每日两次，每次1毫克。对儿童进行了为期3个月的每周随访。结果发现，对于病程少于2年、正在规律服用一种药物或偶尔接受治疗的哮喘儿童，该药有益（尽管益处无统计学意义）。同时服用沙丁胺醇和茶碱但不规律的儿童有轻微效果，而服用泼尼松龙的儿童则无益处。
