缓释茶碱、酮替芬与安慰剂预防幼儿哮喘的对照比较
A controlled comparison of slow-release theophylline, ketotifen and placebo in the prophylaxis of asthma in young children.
作者信息
Carswell F, Stratton D, Hughes A O, Fysh W J, Robinson P
出版信息
Agents Actions Suppl. 1983;13:141-4.
PMID:6346833
Abstract
A double blind crossover comparison of slow-release theophylline, ketotifen and placebo was carried out in 18 young children with perennial asthma. Theophylline significantly reduced symptoms and increased the mean peak expiratory flow rate. Transient nausea and vomiting was commoner during theophylline treatment but did not usually necessitate discontinuance of therapy.
摘要
对18名患有常年性哮喘的幼儿进行了缓释茶碱、酮替芬和安慰剂的双盲交叉对照试验。茶碱显著减轻了症状，并提高了平均呼气峰值流速。在茶碱治疗期间，短暂的恶心和呕吐更为常见，但通常不需要停止治疗。
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