Kresken M, Wiedemann B
Rheinische Friedrich-Wilhelms-Universität, Institut für Medizinische Mikrobiologie und Immunologie, Bonn.
Infection. 1987;15 Suppl 4:S150-7. doi: 10.1007/BF01645862.
In a multicentre study conducted by the Paul-Ehrlich-Gesellschaft we tested about 3,584 clinical isolates from 25 laboratories towards different chemotherapeutics. Using a microdilution test Enterobacteriaceae, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecalis strains regarded as causative pathogens were studied. The data were evaluated for the number, frequency and qualitative characteristics of multiple resistance patterns. None of the strains under test was resistant to all antibiotics tested. Amikacin showed the lowest prevalence of resistance. The significance of such data in the epidemiological control of resistance to chemotherapeutics is discussed.
在保罗 - 埃利希协会开展的一项多中心研究中,我们针对来自25个实验室的约3584株临床分离菌进行了不同化疗药物的测试。采用微量稀释试验,对被视为致病病原体的肠杆菌科细菌、铜绿假单胞菌、金黄色葡萄球菌和粪肠球菌菌株进行了研究。对多重耐药模式的数量、频率和定性特征的数据进行了评估。受试菌株中没有一株对所有测试抗生素都耐药。阿米卡星的耐药率最低。文中讨论了这些数据在化疗药物耐药性流行病学控制中的意义。