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头皮针治疗血管性痴呆患者:一项随机对照试验的系统评价和荟萃分析方案

Scalp acupuncture for patients with vascular dementia: A protocol for systematic review and meta-analysis of randomized controlled trails.

作者信息

Li Jie, Man Qiuhong, Wang Wenchun, Pang Rizhao, Liu Jiancheng, Zhang Feng, Zhang Anren

机构信息

College of Acupuncture & Massage, Shaanxi University of Chinese Medicine, Shaanxi Key Laboratory of Acupuncture & Medicine, Xixian New Area, Shaanxi Province.

Shanghai Fourth People's Hospital Affiliated to Tongji University School of Medicine.

出版信息

Medicine (Baltimore). 2020 Oct 23;99(43):e22798. doi: 10.1097/MD.0000000000022798.

DOI:10.1097/MD.0000000000022798
PMID:33120799
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7581174/
Abstract

BACKGROUND

Vascular dementia (VD) is a kind of acquired intelligence impairment syndrome caused by a series of cerebrovascular factors leading to brain tissue damage. Scalp acupuncture is widely used to treating VD. However, there is no a systematic review has been used to assess the efficacy and safety of scalp acupuncture therapy for VD. Therefore, the purpose of this paper is to systematically evaluate the effects of scalp acupuncture on VD.

METHODS

We will search the following databases from their inception to July 2020: PubMed, Chinese National Knowledge Infrastructure (CNKI), Wan Fang Database, Embase, Medline, Chinese Biomedical Literature Database (CBM), EBSCO, Web of Science, Technology Periodical Database (VIP), the Chongqing VIP Chinese Science and Cochrane Library. At the same time, we will retrieve other resources including conference articles, and gray literature. The randomized controlled trials (RCTs) in English or Chinese associated with scalp acupuncture for VD will be included. Our study data collection and analysis will be conducted independently by 2 reviewers, and Rev Man V.5.3.5 statistical software will be used to performing meta-analysis.

RESULTS

This review research will provide a high-quality synthesis to evaluate the efficacy and safety of scalp acupuncture for patients with VD.

CONCLUSION

This study will provide available evidence to judge whether scalp acupuncture is an effective and safe intervention for patients with VD. It also will provide reliable evidence for its widespread application.

ETHICS AND DISSEMINATION

This systematic review will provide convincing evidence for both patients and clinicians. It does not require ethical approval and the results will be published in a peer-reviewed journal.

OSF REGISTRATION NUMBER

DOI 10.17605/OSF.IO/7CYZR.

摘要

背景

血管性痴呆(VD)是一种由一系列脑血管因素导致脑组织损伤引起的后天性智能障碍综合征。头皮针广泛应用于VD的治疗。然而,尚无系统评价用于评估头皮针治疗VD的疗效和安全性。因此,本文旨在系统评价头皮针对VD的影响。

方法

我们将检索以下数据库自建库至2020年7月的数据:PubMed、中国知网(CNKI)、万方数据库、Embase、Medline、中国生物医学文献数据库(CBM)、EBSCO、科学引文索引(Web of Science)、维普资讯网(VIP)、重庆维普中文科技期刊数据库和考克兰图书馆。同时,我们将检索其他资源,包括会议文章和灰色文献。纳入英文或中文的与头皮针治疗VD相关的随机对照试验(RCT)。本研究的数据收集和分析将由2名评价员独立进行,并使用Rev Man V.5.3.5统计软件进行荟萃分析。

结果

本综述研究将提供高质量的综合评价,以评估头皮针对VD患者的疗效和安全性。

结论

本研究将为判断头皮针是否是治疗VD患者的有效和安全干预措施提供可用证据。它也将为其广泛应用提供可靠证据。

伦理与传播

本系统评价将为患者和临床医生提供有说服力的证据。它不需要伦理批准,结果将发表在同行评审期刊上。

开放科学框架(OSF)注册号:DOI 10.17605/OSF.IO/7CYZR。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4df/7581174/1b22f21dd01d/medi-99-e22798-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4df/7581174/1b22f21dd01d/medi-99-e22798-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4df/7581174/1b22f21dd01d/medi-99-e22798-g002.jpg

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Evaluation of the recovery outcome of poststroke cognitive impairment after cluster needling of scalp acupuncture therapy based on functional near-infrared spectroscopy.基于功能近红外光谱的头针对脑卒中后认知障碍患者针刺治疗后康复效果的评估。
Brain Behav. 2020 Aug;10(8):e01731. doi: 10.1002/brb3.1731. Epub 2020 Jul 8.
2
The effect of combined scalp acupuncture and cognitive training in patients with stroke on cognitive and motor functions.头皮针联合认知训练对脑卒中患者认知和运动功能的影响。
NeuroRehabilitation. 2020;46(1):75-82. doi: 10.3233/NRE-192942.
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Modulatory effect of International Standard Scalp Acupuncture on brain activation in the elderly as revealed by resting-state fMRI.
静息态功能磁共振成像揭示国际标准头皮针疗法对老年人脑激活的调节作用。
Neural Regen Res. 2019 Dec;14(12):2126-2131. doi: 10.4103/1673-5374.262590.
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Acupuncture as a multifunctional neuroprotective therapy ameliorates cognitive impairment in a rat model of vascular dementia: A quantitative iTRAQ proteomics study.针刺作为一种多功能神经保护疗法通过定量 iTRAQ 蛋白质组学研究改善血管性痴呆大鼠模型的认知障碍。
CNS Neurosci Ther. 2018 Dec;24(12):1264-1274. doi: 10.1111/cns.13063. Epub 2018 Oct 2.
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Intensive blood pressure lowering prevents mild cognitive impairment and possible dementia and slows development of white matter lesions in brain: the SPRINT Memory and Cognition IN Decreased Hypertension (SPRINT MIND) study.强化降压可预防轻度认知障碍和可能的痴呆,并减缓大脑白质病变的发展:收缩压干预降低高血压对记忆与认知的影响(SPRINT MIND)研究。
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Neuropharmacology. 2018 May 15;134(Pt B):226-239. doi: 10.1016/j.neuropharm.2017.12.030. Epub 2017 Dec 19.
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