Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), 1-8-31 Midorigaoka, Ikeda, Osaka 563-8577, Japan.
Int J Mol Sci. 2020 Oct 27;21(21):7985. doi: 10.3390/ijms21217985.
Sexual reproduction is almost a universal feature of eukaryotic organisms, which allows the reproduction of new organisms by combining the genetic information from two individuals of different sexes. Based on the mechanism of sexual reproduction, crossbreeding provides an attractive opportunity to improve the traits of animals, plants, and fungi. The budding yeast has been widely utilized in fermentative production since ancient times. Currently it is still used for many essential biotechnological processes including the production of beer, wine, and biofuels. It is surprising that many yeast strains used in the industry exhibit low rates of sporulation resulting in limited crossbreeding efficiency. Here, I provide an overview of the recent findings about infertility challenges of yeasts domesticated for fermentation along with the progress in crossbreeding technologies. The aim of this review is to create an opportunity for future crossbreeding of yeasts used for fermentation.
有性生殖几乎是真核生物的普遍特征，它允许通过将来自不同性别的两个个体的遗传信息结合来繁殖新的生物体。基于有性生殖的机制，杂交提供了一个有吸引力的机会来改善动物、植物和真菌的特性。出芽酵母自古以来就在发酵生产中得到广泛应用。目前，它仍然用于许多重要的生物技术过程，包括啤酒、葡萄酒和生物燃料的生产。令人惊讶的是，工业中使用的许多酵母菌株表现出低的孢子形成率，导致杂交效率有限。在这里，我提供了一个关于为发酵而驯化的酵母的不育性挑战的最新发现的概述，以及在杂交技术方面的进展。本综述的目的是为未来用于发酵的酵母的杂交创造机会。
Zotero 插件