黄斑囊样水肿作为玻璃体视网膜淋巴瘤的首发特征
Cystoid Macular Oedema as a Presenting Feature of Vitreoretinal Lymphoma.
作者信息
Chiu Stephanie, Mudhar Hardeep Singh, Harrison Beth, Spiteri-Cornish Kurt, Sears Katharine
机构信息
Department of Ophthalmology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, United Kingdom.
Department of Histopathology, National Specialist Ophthalmic Pathology Service (NSOPS), Royal Hallamshire Hospital, Sheffield, United Kingdom.
出版信息
Ocul Oncol Pathol. 2020 Oct;6(5):318-322. doi: 10.1159/000508890. Epub 2020 Sep 7.
A 69-year-old female presented with right vitreous cells and cystoid macular oedema (CMO). One year previously, she had received two cycles of attenuated methotrexate-based chemotherapy for primary central nervous system (CNS) lymphoma, abandoned due to toxicity. There was no past ocular history of note aside from mild cataract. Due to her history of previous CNS lymphoma, we suspected vitreoretinal lymphoma (VRL), but the presence of the CMO made this unlikely. She underwent a diagnostic vitrectomy. Histology and immunohistochemistry showed the presence of a high-grade B-cell VRL.
一名69岁女性因右眼玻璃体细胞及黄斑囊样水肿（CMO）就诊。一年前，她因原发性中枢神经系统（CNS）淋巴瘤接受了两个周期以甲氨蝶呤为主的减毒化疗，但因毒性反应而中断。除轻度白内障外，既往无眼部病史。鉴于她之前有中枢神经系统淋巴瘤病史，我们怀疑是玻璃体视网膜淋巴瘤（VRL），但黄斑囊样水肿的存在使这种可能性降低。她接受了诊断性玻璃体切除术。组织学和免疫组化检查显示为高级别B细胞性VRL。
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