Crimi G, Conti G, Candiani A, Antonelli M, Bufi M, Mattia C, Gasparetto A
Institute of Anesthesiology and Resuscitation, University La Sapienza, Rome, Italy.
Intensive Care Med. 1987;13(6):416-8. doi: 10.1007/BF00257687.
In some instances of unilateral acute lung injury (ALI) refractory to conventional ventilatory support, the intact lung is still able to ensure an efficient CO2 washout, the concomitant hypoxaemia being due to the loss of volume of the injured parenchyma. In these cases, the administration of a sufficient selective continuous distending pressure by means of differential continuous positive airway pressure may restore to normal the resting volume and thus the ventilatory performance of the affected lung, contemporarily avoiding the occurrence of pulmonary and systemic barotrauma.
在一些常规通气支持难以奏效的单侧急性肺损伤（ALI）病例中，健侧肺仍能够确保有效的二氧化碳排出，伴随的低氧血症是由于受损实质组织的容积丧失所致。在这些情况下，通过采用不同水平的持续气道正压通气给予足够的选择性持续扩张压力，可能会使患侧肺的静息容积恢复正常，进而恢复其通气功能，同时避免发生肺和全身性气压伤。
