Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
The First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, China.
Int J Gynaecol Obstet. 2021 May;153(2):248-253. doi: 10.1002/ijgo.13453. Epub 2020 Dec 31.
To explore how waiting time after failed fresh cycle embryo transfer affects the pregnancy outcomes of the next frozen embryo transfer (FET).
A retrospective analysis was carried out on the data of women who had received at least one FET after a failed fresh embryo transfer between January 2013 to December 2019. The women were grouped based on the "time" of the first FET, referring to the period between a failed fresh embryo transfer and the beginning of the next cycle of FET. This time is divided into two classes: immediate (<90 days after the failed fresh embryo transfer) and delayed (≥90 days after failed fresh embryo transfer). The following parameters were investigated: clinical pregnancy rate; biochemical pregnancy rate; ectopic pregnancy rate; and non-pregnancy rate.
A total of 293 cases of fresh embryo transfer cycles were included. No significant differences in the number of obtained oocytes, total number of FET, and the total amount of gonadotropin were seen between the immediate and delayed fresh embryo transfer groups. The pregnancy outcomes of the two groups were similar.
The duration of waiting time between failed fresh embryo transfer and the next FET does not affect pregnancy outcomes.
探讨鲜胚移植失败后等待时间对下一次冻胚移植（FET）妊娠结局的影响。
对 2013 年 1 月至 2019 年 12 月期间至少接受过一次 FET 的患者数据进行回顾性分析。根据首次 FET 的“时间”将患者分组，即鲜胚移植失败与下一个 FET 周期开始之间的时间。该时间分为两类：即刻（鲜胚移植失败后<90 天）和延迟（鲜胚移植失败后≥90 天）。调查以下参数：临床妊娠率；生化妊娠率；异位妊娠率；非妊娠率。
共纳入 293 例鲜胚移植周期。即刻和延迟鲜胚移植组的获卵数、FET 总数和促性腺激素总量无显著差异。两组的妊娠结局相似。
鲜胚移植失败与下一次 FET 之间的等待时间长短不会影响妊娠结局。
