Clinical Pharmacy Division, Department of Pharmacy, Faculty of Pharmacy, Mahidol University, 447 Sri-Ayutthaya Road, Ratchathewi, Bangkok, 10400, Thailand.
Centre for Medicines Information and Pharmaceutical Care (CMIPC), Faculty of Pharmacy, Universitas Surabaya, Surabaya, Indonesia.
Int J Clin Pharm. 2021 Jun;43(3):666-672. doi: 10.1007/s11096-020-01178-y. Epub 2020 Oct 29.
BackgroundThere is a limited data in Indonesia regarding the stroke knowledge and medication adherence among stroke survivors.ObjectiveTo assess the level of stroke knowledge and medication adherence along with their relationship among stroke survivors.SettingTwo tertiary-care hospitals in Surabaya, East Java, Indonesia.MethodsA prospective, cross-sectional study was conducted among 215 stroke survivors. Stroke Knowledge Test and the Morisky Green Levine Adherence Scale questionnaires were used to evaluate stroke knowledge and medication adherence, respectively. Binary logistic regression was performed to assess the rela tionship between stroke knowledge and medication adherence. Main outcome measuresRelationship between stroke knowledge and medication adherence.ResultsA total of 215 patients with mean age of 56.34 ± 8.69 years were recruited into this study. Mean Stroke Knowledge Test score was 7.89 ± 3.38 with 76.7% had low level of stroke knowledge. Mean Morisky Green Levine Adherence Scale was 3.05 ± 1.11 with 52.1% had low to medium medication adherence. Education and duration of stroke correlated with stroke knowledge level (Spearman's correlation coefficient: 0.307, p = 0.001 and 0.128, p = 0.041, respectively). Age and disability correlated with medication adherence (Spearman's correlation coefficient: 0.169; p = 0.013 and 0.171; p = 0.012), respectively. After adjustment for covariates, stroke knowledge level was independently associated with medication adherence (adjusted OR: 4.37, 95% CI 2.00-9.53; p < 0.001).ConclusionStroke knowledge was low among Indonesian stroke survivors and independently related to medication adherence. Attempts should be made to increase stroke knowledge which may improve medication adherence among stroke survivors.
印度尼西亚关于中风患者的中风知识和药物依从性的数据有限。
评估中风幸存者的中风知识水平和药物依从性及其之间的关系。
印度尼西亚东爪哇省泗水的两家三级保健医院。
对 215 名中风幸存者进行前瞻性、横断面研究。使用中风知识测试和 Morisky Green Levine 依从性量表问卷分别评估中风知识和药物依从性。进行二元逻辑回归分析以评估中风知识和药物依从性之间的关系。
中风知识和药物依从性之间的关系。
共纳入 215 名平均年龄为 56.34±8.69 岁的患者。平均中风知识测试得分为 7.89±3.38,76.7%的患者中风知识水平较低。平均 Morisky Green Levine 依从性量表评分为 3.05±1.11,52.1%的患者药物依从性为低至中等。教育程度和中风持续时间与中风知识水平相关(Spearman 相关系数:0.307,p=0.001 和 0.128,p=0.041)。年龄和残疾与药物依从性相关(Spearman 相关系数:0.169;p=0.013 和 0.171;p=0.012)。调整协变量后,中风知识水平与药物依从性独立相关(调整后的优势比:4.37,95%置信区间 2.00-9.53;p<0.001)。
印度尼西亚中风幸存者的中风知识水平较低,与药物依从性独立相关。应努力提高中风知识水平,从而提高中风幸存者的药物依从性。