Ouslander J G, Greengold B, Chen S
Veterans Administration Medical Center, Sepulveda, California.
J Urol. 1987 Nov;138(5):1191-5. doi: 10.1016/s0022-5347(17)43546-4.
We studied prospectively the incidence of symptomatic infections of presumed urinary tract origin requiring antimicrobial therapy among 54 male nursing home patients with chronic indwelling bladder catheters. During 514 patient-months at risk there were 106 episodes of symptomatic infection, for an incidence of 0.21 per patient-month at risk. Of the patients 80 per cent had at least 1 episode and 48 per cent had 2 or more. None of the clinical factors we examined, including age, nutritional status, stool incontinence, diabetes mellitus, episodes of catheter blockage and the use of chronic suppressant antimicrobial therapy, was associated with the development of symptomatic infection. Further research on host and pathogen-related factors that increase the risk for symptomatic infection, and improvements in infection control and catheter care protocols are necessary to decrease catheter-associated morbidity among male nursing home patients who must be managed by chronic indwelling catheterization.
我们前瞻性地研究了54例长期留置膀胱导尿管的男性疗养院患者中，需要抗菌治疗的疑似尿路感染症状性感染的发生率。在514个患者月的风险期内，有106次症状性感染发作，风险期内每位患者每月的发生率为0.21。80%的患者至少有1次发作，48%的患者有2次或更多次发作。我们检查的所有临床因素，包括年龄、营养状况、大便失禁、糖尿病、导尿管堵塞发作以及长期使用抑制性抗菌治疗，均与症状性感染的发生无关。有必要进一步研究增加症状性感染风险的宿主和病原体相关因素，并改进感染控制和导尿管护理方案，以降低必须通过长期留置导尿管理的男性疗养院患者中与导尿管相关的发病率。
