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老年患者导尿管相关感染的预防与治疗

Prevention and treatment of urinary catheter-related infections in older patients.

作者信息

Nicolle L E

机构信息

Department of Internal Medicine, University of Manitoba, Winnipeg, Canada.

出版信息

Drugs Aging. 1994 May;4(5):379-91. doi: 10.2165/00002512-199404050-00003.

Abstract

The elderly population is more likely to have urinary catheters used than younger populations. Most patients with short term indwelling catheters (those in place less than 30 days) will be residents of acute care institutions. The frequency of catheter-acquired bacteriuria is greater with longer durations of catheterisation, female gender, failure to maintain a closed drainage system, and in patients not receiving systemic antimicrobials. Systemic antimicrobials given within 48 hours of catheter removal decrease the incidence of urinary infection, but are not currently recommended because of concerns with antimicrobial resistance. Interventions such as topical meatal antimicrobials, disinfectants added to the urinary drainage bag, antimicrobial coatings for catheters, and antimicrobial irrigation have not been shown to decrease the incidence of infection. Asymptomatic bacteriuria should not be treated while the catheter remains in place. However, catheter-acquired bacteriuria should probably be treated following catheter removal. Long term indwelling catheters are most frequently used in elderly individuals resident in long term care institutions. These individuals are always bacteriuric, usually with a complex polymicrobial flora. There are no clinical benefits of treatment of asymptomatic bacteriuria in such persons. In fact, treatment will promote the emergence of resistant organisms. The optimal management of symptomatic infection has not been defined.

摘要

与年轻人群相比,老年人群使用导尿管的可能性更高。大多数短期留置导尿管的患者(导尿管留置时间少于30天)是急性护理机构的住院患者。导尿管留置时间越长、女性、未维持封闭引流系统以及未接受全身性抗菌药物治疗的患者,导管相关菌尿的发生率越高。在拔除导尿管后48小时内给予全身性抗菌药物可降低泌尿系统感染的发生率,但由于担心抗菌药物耐药性,目前不推荐使用。局部尿道口抗菌药物、在尿液引流袋中添加消毒剂、导尿管抗菌涂层以及抗菌冲洗等干预措施尚未显示可降低感染发生率。导尿管留置期间,无症状菌尿不应进行治疗。然而,导尿管拔除后,导管相关菌尿可能需要治疗。长期留置导尿管最常用于长期护理机构中的老年人。这些人通常总有菌尿,通常伴有复杂的多种微生物菌群。对此类人群的无症状菌尿进行治疗没有临床益处。事实上,治疗会促使耐药菌出现。有症状感染的最佳管理方法尚未确定。

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