Guthrie Clinic, Trauma & Surgical Critical Care, Sayre, Pennsylvania.
University of Virginia, Biochemistry and Molecular Genetics, Charlottesville, Virginia.
J Surg Res. 2021 Mar;259:487-492. doi: 10.1016/j.jss.2020.09.017. Epub 2020 Oct 28.
Adhesive small bowel obstruction (ASBO) has classically been managed with nasogastric tube decompression and watchful waiting. Our group developed an evidence-based protocol to manage ASBO utilizing a water-soluble contrast (WSC) agent. We hypothesized the protocol would decrease the length of stay (LOS) for patients admitted with ASBO along with the time interval from admission to surgery.
From 2010 to 2018, a retrospective review was performed, including all patients admitted with a diagnosis of ASBO. These patients were divided into two groups: the preprotocol group included years 2010-2013 and the postprotocol group included years 2015-2018. A Student t-test and a two-proportion z-test were used for statistical analysis.
We captured 767 patients; 296 in the preprotocol group and 471 in the postprotocol group. We found a significant decrease in overall LOS between the preprotocol and postprotocol groups (6.56 d versus 4.08 d; P < 0.001) along with decreases in LOS for patients managed nonoperatively (5.36 d versus 3.42 d; P < 0.001) and operatively (16.09 d versus 9.47 d; P < 0.001). Time interval from admission to the operation was significantly decreased in the postprotocol group (3.79 d versus 2.10 d; P < 0.050). We identified a trend toward decreased rates of bowel ischemia and resections with our protocol.
These results reaffirm previous reports of WSC's impact on overall LOS in ASBO while showing a similar impact on both operative and nonoperative groups. The decreased time interval between admission and operation may impact the incidence of bowel ischemia and resections.
黏连性小肠梗阻(ASBO)传统上采用鼻胃管减压和密切观察治疗。我们的团队制定了一项基于证据的协议,通过使用水溶性对比剂(WSC)来管理 ASBO。我们假设该协议将降低因 ASBO 住院患者的住院时间(LOS)以及从入院到手术的时间间隔。
回顾性分析 2010 年至 2018 年期间所有因 ASBO 入院的患者。这些患者分为两组:协议前组包括 2010 年至 2013 年,协议后组包括 2015 年至 2018 年。采用学生 t 检验和两比例 z 检验进行统计学分析。
共纳入 767 例患者,其中协议前组 296 例,协议后组 471 例。与协议前组相比,协议后组总 LOS 明显缩短(6.56 天比 4.08 天;P<0.001),非手术治疗组 LOS 缩短(5.36 天比 3.42 天;P<0.001),手术治疗组 LOS 缩短(16.09 天比 9.47 天;P<0.001)。协议后组入院至手术时间间隔明显缩短(3.79 天比 2.10 天;P<0.050)。我们发现该协议有降低肠缺血和肠切除率的趋势。
这些结果证实了先前关于 WSC 对 ASBO 总 LOS 影响的报告,同时表明该协议对手术和非手术组均有类似影响。入院与手术之间的时间间隔缩短可能会影响肠缺血和肠切除的发生率。