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粘连性小肠梗阻管理算法的可行性与安全性

Feasibility and safety of an algorithm for the management of adhesive small bowel obstruction.

作者信息

Chappalley Dimitri, Dupasquier Nicolas, Heierli Gabriel, Torres Maria Teresa, Hahnloser Dieter, Grass Fabian, Hübner Martin

机构信息

Department of Visceral Surgery, University Hospital Lausanne (CHUV), University of Lausanne (UNIL), Rue du Bugnon 46, Lausanne, 1011, Switzerland.

出版信息

Langenbecks Arch Surg. 2025 Sep 3;410(1):262. doi: 10.1007/s00423-025-03820-7.

Abstract

INTRODUCTION

This single-center, prospective cohort study assessed the feasibility and safety of a structured management protocol (Ileus Management Algorithm Protocol: I-MAP) for patients with adhesive small bowel obstruction (ASBO).

METHOD

Among 63 patients initially admitted for ASBO, 40 met the inclusion criteria and were managed in line with I-MAP, incorporating nasogastric tube (NGT) output and water-soluble contrast (WSC) administration within a standardized decision-making framework.

RESULTS

The study's primary outcome, protocol adherence, was achieved in 87.5% (35/40) of patients, demonstrating the protocol's feasibility. 27/35 patients (77%) had ASBO resolution with conservative management. Eight patients required surgery, mostly due to lack of improvement after 72 hours of conservative management. Complications were minimal, with only two cases of bronchial aspiration. No patient died within 30 days of conservative management.

CONCLUSION

This standardized algorithm using pre-defined NGT output values proved feasible and safe, standardizing care and providing structured guidance in clinical decision-making. Larger trials are necessary to confirm efficacy and explore patient-reported outcomes.

摘要

引言

这项单中心前瞻性队列研究评估了粘连性小肠梗阻(ASBO)患者结构化管理方案(肠梗阻管理算法方案:I-MAP)的可行性和安全性。

方法

在最初因ASBO入院的63例患者中,40例符合纳入标准,并按照I-MAP进行管理,在标准化决策框架内纳入鼻胃管(NGT)引流和水溶性造影剂(WSC)给药。

结果

该研究的主要结局,即方案依从性,在87.5%(35/40)的患者中实现,证明了该方案的可行性。27/35例患者(77%)通过保守治疗使ASBO得到缓解。8例患者需要手术,主要原因是保守治疗72小时后病情无改善。并发症极少,仅有2例支气管误吸。保守治疗30天内无患者死亡。

结论

这种使用预定义NGT引流值的标准化算法被证明是可行和安全的,规范了护理并为临床决策提供了结构化指导。需要进行更大规模的试验来证实疗效并探索患者报告的结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e78e/12408694/dc403b2e1089/423_2025_3820_Fig1_HTML.jpg

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