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甲磺酸去铁胺治疗肾周囊肿的初步经验。

The preliminary experience of methylene blue assisted laparoscopy in the treatment of renal parapelvic cysts.

机构信息

Department of Urology, Tianjin Third Central Hospital, NO.83 Jintang Road, Hedong District, Tianjin, 300170, China.

出版信息

Sci Rep. 2020 Oct 30;10(1):18757. doi: 10.1038/s41598-020-76006-4.

DOI:10.1038/s41598-020-76006-4
PMID:33128007
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7599209/
Abstract

Renal cyst is a common disease in humans and laparoscopic renal cyst decortication is the gold standard for treatment. However, specialized surgical skills are required for the treatment of renal parapelvic cysts. In this study, we describe an improved laparoscopic method for the treatment of renal parapelvic cysts involving the use of continuous infusion of methylene blue. Sixteen patients with renal parapelvic cyst were enrolled in this study. All patients underwent retrograde ureteral catheterization, with continuous perfusion of the renal pelvis using a solution of 0.2% methylene blue and saline, during laparoscopic decortication of the parapelvic cyst. In one patient, the cyst communicated with the renal collection system which was injured, but this was immediately repaired intraoperatively. All operations were successful, and none was converted to open surgery. There were no occurrences of persistent urinary fistula, bleeding, or other complications postoperatively. All patients were followed-up for 3-24 months, and results of postoperative imaging investigations revealed that all of our patients experienced either complete recovery or a greater than 50% decrease in size of the cysts. Our study demonstrates that methylene blue-assisted laparoscopic treatment is a safe, effective and practical method for the treatment of renal parapelvic cysts.

摘要

肾囊肿是人类的一种常见疾病,腹腔镜肾囊肿去顶术是治疗该病的金标准。然而,治疗肾盂旁囊肿需要专业的手术技能。在这项研究中,我们描述了一种改良的腹腔镜治疗肾盂旁囊肿的方法,该方法涉及使用亚甲蓝持续输注。本研究纳入了 16 例肾盂旁囊肿患者。所有患者均在腹腔镜下进行肾盂旁囊肿去顶术时接受逆行输尿管置管术,用 0.2%亚甲蓝和生理盐水溶液持续灌注肾盂。在 1 例患者中,囊肿与肾盂集合系统相通并被损伤,但术中立即进行了修复。所有手术均成功完成,无一例转为开放性手术。术后无持续性尿瘘、出血或其他并发症发生。所有患者均随访 3-24 个月,术后影像学检查结果显示,所有患者的囊肿均完全消退或缩小超过 50%。本研究表明,亚甲蓝辅助腹腔镜治疗是一种安全、有效、实用的治疗肾盂旁囊肿的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d28/7599209/6871e5f970cf/41598_2020_76006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d28/7599209/6871e5f970cf/41598_2020_76006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d28/7599209/6871e5f970cf/41598_2020_76006_Fig1_HTML.jpg

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J Laparoendosc Adv Surg Tech A. 2020 Apr;30(4):471-476. doi: 10.1089/lap.2019.0650. Epub 2020 Mar 12.
2
Methylene Blue Injection via Percutaneous Renal Cyst Puncture Used in Flexible Ureteroscope for Treatment of Parapelvic Cysts: A Modified Method for Easily Locating Cystic Wall.经皮肾囊肿穿刺注射亚甲蓝在输尿管软镜治疗肾盂旁囊肿中的应用:一种易于定位囊壁的改良方法
Urology. 2019 Mar;125:243-247. doi: 10.1016/j.urology.2018.11.014. Epub 2018 Nov 16.
3
Giant renal parapelvic cyst with pelvi-ureteric junction obstruction in an infant: challenges in diagnosis and laparoscopic management.
婴儿巨大肾盂旁囊肿合并肾盂输尿管交界处梗阻:诊断和腹腔镜治疗的挑战。
BMJ Case Rep. 2022 May 11;15(5):e249548. doi: 10.1136/bcr-2022-249548.
Simultaneous treatment of parapelvic renal cysts and stones by flexible ureterorenoscopy with a novel four-step cyst localization strategy.
采用新型四步囊肿定位策略的输尿管软镜同期治疗肾盂旁囊肿和结石。
Int Braz J Urol. 2018 Sep-Oct;44(5):958-964. doi: 10.1590/S1677-5538.IBJU.2018.0074.
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Non-conservative management of simple renal cysts in adults: a comprehensive review of literature.成人单纯性肾囊肿的非保守治疗:文献综述
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