Applied Parasitology Laboratory, Animal Science Department, Federal University of Maranhão, Chapadinha, MA, Brazil.
Protozoology Laboratory, Preventive Veterinary Medicine Department, State University of Londrina, Londrina, PR, Brazil.
Prev Vet Med. 2020 Dec;185:105176. doi: 10.1016/j.prevetmed.2020.105176. Epub 2020 Oct 10.
This meta-analysis aimed to estimate N. caninum seroprevalence in goats worldwide to determine the main risk factors for seropositivity that could be associated with parasite infection in herds. Four electronic databases were searched: PubMed, SciELO, Scopus and the VHL Regional Portal. Firstly, 367 articles were identified. After removing duplicates and non-eligible papers. A total of 36 articles were selected, which contained information concerning 22,234 goats, between 2004-2019. The combined seroprevalence of infection using a meta-analysis of the random effects model was 5.99 % (95 %, CI 4.38-7.83). The overall estimated N. caninum seroprevalence showed high heterogeneity, I = 97 %. The present study showed that seropositive goats were 3.07 times more likely to abort (OR 3.07; 95 % CI 1.02-9.22) than seronegative animals. The presence of dogs on farms also increased the odds of N. caninum seropositivity (OR 1.40; 95 % CI 1.01-1.94). In addition, male animals had higher odds of being seropositive to neosporosis than females (OR 1.31; 95 % CI 1.00-1.71). N. caninum seroprevalence in goats is widely distributed worldwide, with the American continent having a higher proportion of seropositive animals.
本荟萃分析旨在估计全球山羊中 N. caninum 的血清流行率，以确定与畜群寄生虫感染相关的主要血清阳性风险因素。检索了四个电子数据库：PubMed、SciELO、Scopus 和 VHL 区域门户。首先，确定了 367 篇文章。在去除重复项和不合格的论文后，共选择了 36 篇文章，其中包含了 2004-2019 年间 22234 只山羊的信息。使用随机效应模型的荟萃分析计算感染的综合血清流行率为 5.99%（95%CI 4.38-7.83）。总体估计的 N. caninum 血清流行率显示出高度异质性，I = 97%。本研究表明，血清阳性的山羊流产的可能性是血清阴性动物的 3.07 倍（OR 3.07；95%CI 1.02-9.22）。农场中存在狗也会增加 N. caninum 血清阳性的几率（OR 1.40；95%CI 1.01-1.94）。此外，雄性动物感染新孢子虫的几率高于雌性动物（OR 1.31；95%CI 1.00-1.71）。全球范围内，山羊中 N. caninum 的血清流行率广泛分布，美洲大陆的血清阳性动物比例更高。
Zotero 插件